Ultrawide field, distortion-corrected ocular shape estimation with MHz optical coherence tomography (OCT).

Journal Article (Journal Article)

Ocular deformation may be associated with biomechanical alterations in the structures of the eye, especially the cornea and sclera in conditions such as keratoconus, congenital glaucoma, and pathological myopia. Here, we propose a method to estimate ocular shape using an ultra-wide field MHz swept-source optical coherence tomography (SS-OCT) with a Fourier Domain Mode-Locked (FDML) laser and distortion correction of the images. The ocular biometrics for distortion correction was collected by an IOLMaster 700, and localized Gaussian curvature was proposed to quantify the ocular curvature covering a field-of-view up to 65°×62°. We achieved repeatable curvature shape measurements (intraclass coefficient = 0.88 ± 0.06) and demonstrated its applicability in a pilot study with individuals (N = 11) with various degrees of myopia.

Full Text

Duke Authors

Cited Authors

  • Tan, B; McNabb, RP; Zheng, F; Sim, YC; Yao, X; Chua, J; Ang, M; Hoang, QV; Kuo, AN; Schmetterer, L

Published Date

  • September 1, 2021

Published In

Volume / Issue

  • 12 / 9

Start / End Page

  • 5770 - 5781

PubMed ID

  • 34692214

Pubmed Central ID

  • PMC8515957

International Standard Serial Number (ISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/BOE.428430


  • eng

Conference Location

  • United States