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Opioid Induced Hyperalgesia.

Publication ,  Journal Article
Yi, P; Pryzbylkowski, P
Published in: Pain Med
October 2015

OBJECTIVE: To discuss the phenomenon of opioid induced hyperalgesia (OIH) and investigate the data and clinical recommendations available on this topic. DESIGN: A literature search on the topic of OIH was performed. Relevant studies pertaining to OIH were included in this review. RESULTS: Existing studies and reviews on the pathophysiology, diagnosis, and clinical management of OIH are discussed with updated data and literature references. CONCLUSION: As more opioids are prescribed, especially to treat chronic nonmalignant pain, OIH becomes more of a relevant and significant issue. Although the exact mechanisms of OIH are not clearly understood further research is required to broaden and develop our knowledge of this topic.

Duke Scholars

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Published In

Pain Med

DOI

EISSN

1526-4637

Publication Date

October 2015

Volume

16 Suppl 1

Start / End Page

S32 / S36

Location

England

Related Subject Headings

  • Opioid-Related Disorders
  • Hyperalgesia
  • Humans
  • Drug Tolerance
  • Disease Models, Animal
  • Chronic Pain
  • Animals
  • Anesthesiology
  • Analgesics, Opioid
  • 5203 Clinical and health psychology
 

Citation

APA
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ICMJE
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Yi, P., & Pryzbylkowski, P. (2015). Opioid Induced Hyperalgesia. Pain Med, 16 Suppl 1, S32–S36. https://doi.org/10.1111/pme.12914
Yi, Peter, and Peter Pryzbylkowski. “Opioid Induced Hyperalgesia.Pain Med 16 Suppl 1 (October 2015): S32–36. https://doi.org/10.1111/pme.12914.
Yi P, Pryzbylkowski P. Opioid Induced Hyperalgesia. Pain Med. 2015 Oct;16 Suppl 1:S32–6.
Yi, Peter, and Peter Pryzbylkowski. “Opioid Induced Hyperalgesia.Pain Med, vol. 16 Suppl 1, Oct. 2015, pp. S32–36. Pubmed, doi:10.1111/pme.12914.
Yi P, Pryzbylkowski P. Opioid Induced Hyperalgesia. Pain Med. 2015 Oct;16 Suppl 1:S32–S36.
Journal cover image

Published In

Pain Med

DOI

EISSN

1526-4637

Publication Date

October 2015

Volume

16 Suppl 1

Start / End Page

S32 / S36

Location

England

Related Subject Headings

  • Opioid-Related Disorders
  • Hyperalgesia
  • Humans
  • Drug Tolerance
  • Disease Models, Animal
  • Chronic Pain
  • Animals
  • Anesthesiology
  • Analgesics, Opioid
  • 5203 Clinical and health psychology