Evolution of Focal Therapy in Prostate Cancer: Past, Present, and Future.

Journal Article (Journal Article;Review)

Organ sparing approaches for the management of localized prostate cancer were developed in part to overcome the morbidity associated with standard, whole gland treatment options. The first description of focal therapy was now over two decades ago and since that time much has changed. The evolution of patient selection, the approach to ablation, and surveillance after focal therapy have mirrored the technologic advancements in the field as well as the improved understanding of the biology of low-grade, low-risk prostate cancer. This review presents the evidence for the basis of focal therapy from the past to the present and future endeavors.

Full Text

Duke Authors

Cited Authors

  • Arcot, R; Polascik, TJ

Published Date

  • February 2022

Published In

Volume / Issue

  • 49 / 1

Start / End Page

  • 129 - 152

PubMed ID

  • 34776047

Electronic International Standard Serial Number (EISSN)

  • 1558-318X

Digital Object Identifier (DOI)

  • 10.1016/j.ucl.2021.07.011


  • eng

Conference Location

  • United States