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Longevity and stress in Caenorhabditis elegans.

Publication ,  Journal Article
Zhou, KI; Pincus, Z; Slack, FJ
Published in: Aging
August 2011

It has long been understood that many of the same manipulations that increase longevity in Caenorhabditis elegans also increase resistance to various acute stressors, and vice-versa; moreover these findings hold in more complex organisms as well. Nevertheless, the mechanistic relationship between these phenotypes remains unclear, and in many cases the overlap between stress resistance and longevity is inexact. Here we review the known connections between stress resistance and longevity, discuss instances in which these connections are absent, and summarize the theoretical explanations that have been posited for these phenomena.

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Published In

Aging

DOI

EISSN

1945-4589

ISSN

1945-4589

Publication Date

August 2011

Volume

3

Issue

8

Start / End Page

733 / 753

Related Subject Headings

  • Stress, Physiological
  • Longevity
  • Hot Temperature
  • Gene Expression Regulation
  • Developmental Biology
  • Caenorhabditis elegans
  • Animals
  • 1112 Oncology and Carcinogenesis
  • 0606 Physiology
  • 0601 Biochemistry and Cell Biology
 

Citation

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Zhou, K. I., Pincus, Z., & Slack, F. J. (2011). Longevity and stress in Caenorhabditis elegans. Aging, 3(8), 733–753. https://doi.org/10.18632/aging.100367
Zhou, Katherine I., Zachary Pincus, and Frank J. Slack. “Longevity and stress in Caenorhabditis elegans.Aging 3, no. 8 (August 2011): 733–53. https://doi.org/10.18632/aging.100367.
Zhou KI, Pincus Z, Slack FJ. Longevity and stress in Caenorhabditis elegans. Aging. 2011 Aug;3(8):733–53.
Zhou, Katherine I., et al. “Longevity and stress in Caenorhabditis elegans.Aging, vol. 3, no. 8, Aug. 2011, pp. 733–53. Epmc, doi:10.18632/aging.100367.
Zhou KI, Pincus Z, Slack FJ. Longevity and stress in Caenorhabditis elegans. Aging. 2011 Aug;3(8):733–753.

Published In

Aging

DOI

EISSN

1945-4589

ISSN

1945-4589

Publication Date

August 2011

Volume

3

Issue

8

Start / End Page

733 / 753

Related Subject Headings

  • Stress, Physiological
  • Longevity
  • Hot Temperature
  • Gene Expression Regulation
  • Developmental Biology
  • Caenorhabditis elegans
  • Animals
  • 1112 Oncology and Carcinogenesis
  • 0606 Physiology
  • 0601 Biochemistry and Cell Biology