Creation and Implementation of a Preoperative Malignant Hyperthermia Screening Tool.

Journal Article (Journal Article)


Malignant hyperthermia (MH) is a potentially lethal pharmacogenetic disorder triggered by certain anesthetic agents. There is currently no standardized preoperative screening tool utilized to identify MH-susceptible individuals.

Local problem

This quality improvement (QI) project aimed to enhance preoperative screening for MH susceptibility (MHS) by implementing an evidence-based screening tool for surgical patients at 2 sites.


This prospective descriptive QI project evaluated the success of implementing an MHS screening tool preoperatively and its impact on the anesthesia plan.


Anesthesia professionals included the screening tool in their preoperative interview for surgical patients so that positively screened patients could receive MH prevention measures.


A total of 95 patients at site A and 234 patients at site B were screened using the MH tool, a cumulative total of 21 patients were positively screened, and 1 anesthetic plan was altered.


This MHS screening tool has the potential to prevent MH episodes when used consistently by staff.

Full Text

Duke Authors

Cited Authors

  • Johnson, T; Simmons, VC; Figer Schwartz, S; Tola, DH

Published Date

  • July 2022

Published In

Volume / Issue

  • 37 / 3

Start / End Page

  • 269 - 274

PubMed ID

  • 34799529

Electronic International Standard Serial Number (EISSN)

  • 1550-5065

International Standard Serial Number (ISSN)

  • 1057-3631

Digital Object Identifier (DOI)

  • 10.1097/ncq.0000000000000610


  • eng