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Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM.

Publication ,  Journal Article
Chen, SC-A; Perfect, J; Colombo, AL; Cornely, OA; Groll, AH; Seidel, D; Albus, K; de Almedia, JN; Garcia-Effron, G; Gilroy, N; Lass-Flörl, C ...
Published in: Lancet Infect Dis
December 2021

Uncommon, or rare, yeast infections are on the rise given increasing numbers of patients who are immunocompromised or seriously ill. The major pathogens include those of the genera Geotrichum, Saprochaete, Magnusiomyces, and Trichosporon (ie, basidiomycetes) and Kodamaea, Malassezia, Pseudozyma (ie, now Moesziomyces or Dirkmeia), Rhodotorula, Saccharomyces, and Sporobolomyces (ie, ascomycetes). A considered approach to the complex, multidisciplinary management of infections that are caused by these pathogens is essential to optimising patient outcomes; however, management guidelines are either region-specific or require updating. In alignment with the One World-One Guideline initiative to incorporate regional differences, experts from diverse geographical regions analysed publications describing the epidemiology and management of the previously mentioned rare yeasts. This guideline summarises the consensus recommendations with regards to the diagnostic and therapeutic options for patients with these rare yeast infections, with the intent of providing practical assistance in clinical decision making. Because there is less clinical experience of patients with rare yeast infections and studies on these patients were not randomised, nor were groups compared, most recommendations are not robust in their validation but represent insights by use of expert opinions and in-vitro susceptibility results. In this Review, we report the key features of the epidemiology, diagnosis, antifungal susceptibility, and treatment outcomes of patients with Geotrichum, Saprochaete, Magnusiomyces, and Trichosporon spp infections.

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Published In

Lancet Infect Dis

DOI

EISSN

1474-4457

Publication Date

December 2021

Volume

21

Issue

12

Start / End Page

e375 / e386

Location

United States

Related Subject Headings

  • Mycoses
  • Mitosporic Fungi
  • Microbiology
  • Immunocompromised Host
  • Humans
  • Guidelines as Topic
  • Global Health
  • Ascomycota
  • Antifungal Agents
  • 4202 Epidemiology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chen, S.-A., Perfect, J., Colombo, A. L., Cornely, O. A., Groll, A. H., Seidel, D., … Govender, N. P. (2021). Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis, 21(12), e375–e386. https://doi.org/10.1016/S1473-3099(21)00203-6
Chen, Sharon C-A, John Perfect, Arnaldo L. Colombo, Oliver A. Cornely, Andreas H. Groll, Danila Seidel, Kerstin Albus, et al. “Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM.Lancet Infect Dis 21, no. 12 (December 2021): e375–86. https://doi.org/10.1016/S1473-3099(21)00203-6.
Chen SC-A, Perfect J, Colombo AL, Cornely OA, Groll AH, Seidel D, et al. Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis. 2021 Dec;21(12):e375–86.
Chen, Sharon C. A., et al. “Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM.Lancet Infect Dis, vol. 21, no. 12, Dec. 2021, pp. e375–86. Pubmed, doi:10.1016/S1473-3099(21)00203-6.
Chen SC-A, Perfect J, Colombo AL, Cornely OA, Groll AH, Seidel D, Albus K, de Almedia JN, Garcia-Effron G, Gilroy N, Lass-Flörl C, Ostrosky-Zeichner L, Pagano L, Papp T, Rautemaa-Richardson R, Salmanton-García J, Spec A, Steinmann J, Arikan-Akdagli S, Arenz DE, Sprute R, Duran-Graeff L, Freiberger T, Girmenia C, Harris M, Kanj SS, Roudbary M, Lortholary O, Meletiadis J, Segal E, Tuon FF, Wiederhold N, Bicanic T, Chander J, Chen Y-C, Hsueh P-R, Ip M, Munoz P, Spriet I, Temfack E, Thompson L, Tortorano AM, Velegraki A, Govender NP. Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis. 2021 Dec;21(12):e375–e386.
Journal cover image

Published In

Lancet Infect Dis

DOI

EISSN

1474-4457

Publication Date

December 2021

Volume

21

Issue

12

Start / End Page

e375 / e386

Location

United States

Related Subject Headings

  • Mycoses
  • Mitosporic Fungi
  • Microbiology
  • Immunocompromised Host
  • Humans
  • Guidelines as Topic
  • Global Health
  • Ascomycota
  • Antifungal Agents
  • 4202 Epidemiology