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Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States.

Publication ,  Journal Article
Gupta, K; Girotra, S; Nallamothu, BK; Kennedy, K; Starks, MA; Chan, PS ...
Published in: Resuscitation
January 2022

BACKGROUND: Studies have reported lower survival for in-hospital cardiac arrest (IHCA) during the initial COVID-19 surge. Whether the pandemic reduced IHCA survival during subsequent surges and in areas with lower COVID-19 rates is unknown. METHODS: Within Get-With-The-Guidelines®-Resuscitation, we identified 22,899 and 79,736 IHCAs during March to December in 2020 and 2015-2019, respectively. Using hierarchical regression, we compared risk-adjusted rates of survival to discharge in 2020 vs. 2015-19 during five COVID-19 periods: Surge 1 (March to mid-May), post-Surge 1 (mid-May to June), Surge 2 (July to mid-August), post-Surge 2 (mid-August to mid-October), and Surge 3 (mid-October to December). Monthly COVID-19 mortality rates for each hospital's county were categorized, per 1,000,000 residents, as very low (0-10), low (11-50), moderate (51-100), or high (>100). RESULTS: During each COVID-19 surge period in 2020, rates of survival to discharge for IHCA were lower, as compared with the same period in 2015-2019: Surge 1: adjusted OR: 0.81 (0.75-0.88); Surge 2: adjusted OR: 0.88 (0.79-0.97), Surge 3: adjusted OR: 0.79 (0.73-0.86). Lower survival was most pronounced at hospitals located in counties with moderate to high monthly COVID-19 mortality rates. In contrast, during the two post-surge periods, survival rates were similar in 2020 vs. 2015-2019: post-Surge 1: adjusted OR 0.93 (0.83-1.04) and post-Surge 2: adjusted OR 0.94 (0.86-1.03), even at hospitals with the highest county-level COVID-19 mortality rates. CONCLUSIONS: During the three COVID-19 surges in the U.S. during 2020, rates of survival to discharge for IHCA dropped substantially, especially in communities with moderate to high COVID-19 mortality rates.

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Published In

Resuscitation

DOI

EISSN

1873-1570

Publication Date

January 2022

Volume

170

Start / End Page

134 / 140

Location

Ireland

Related Subject Headings

  • United States
  • Survival Rate
  • SARS-CoV-2
  • Pandemics
  • Humans
  • Hospitals
  • Heart Arrest
  • Emergency & Critical Care Medicine
  • Cardiopulmonary Resuscitation
  • COVID-19
 

Citation

APA
Chicago
ICMJE
MLA
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Gupta, K., Girotra, S., Nallamothu, B. K., Kennedy, K., Starks, M. A., Chan, P. S., & American Heart Association’s Get With the Guidelines®-Resuscitation Investigators (listed in Supplementary Appendix), . (2022). Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States. Resuscitation, 170, 134–140. https://doi.org/10.1016/j.resuscitation.2021.11.025
Gupta, Kashvi, Saket Girotra, Brahmajee K. Nallamothu, Kevin Kennedy, Monique A. Starks, Paul S. Chan, and Paul S. American Heart Association’s Get With the Guidelines®-Resuscitation Investigators (listed in Supplementary Appendix). “Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States.Resuscitation 170 (January 2022): 134–40. https://doi.org/10.1016/j.resuscitation.2021.11.025.
Gupta K, Girotra S, Nallamothu BK, Kennedy K, Starks MA, Chan PS, et al. Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States. Resuscitation. 2022 Jan;170:134–40.
Gupta, Kashvi, et al. “Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States.Resuscitation, vol. 170, Jan. 2022, pp. 134–40. Pubmed, doi:10.1016/j.resuscitation.2021.11.025.
Gupta K, Girotra S, Nallamothu BK, Kennedy K, Starks MA, Chan PS, American Heart Association’s Get With the Guidelines®-Resuscitation Investigators (listed in Supplementary Appendix). Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States. Resuscitation. 2022 Jan;170:134–140.
Journal cover image

Published In

Resuscitation

DOI

EISSN

1873-1570

Publication Date

January 2022

Volume

170

Start / End Page

134 / 140

Location

Ireland

Related Subject Headings

  • United States
  • Survival Rate
  • SARS-CoV-2
  • Pandemics
  • Humans
  • Hospitals
  • Heart Arrest
  • Emergency & Critical Care Medicine
  • Cardiopulmonary Resuscitation
  • COVID-19