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Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.

Publication ,  Journal Article
Gordon, MN; Heneka, MT; Le Page, LM; Limberger, C; Morgan, D; Tenner, AJ; Terrando, N; Willette, AA; Willette, SA
Published in: Alzheimers Dement
May 2022

COVID-19 causes lasting neurological symptoms in some survivors. Like other infections, COVID-19 may increase risk of cognitive impairment. This perspective highlights four knowledge gaps about COVID-19 that need to be filled to avoid this possible health issue. The first is the need to identify the COVID-19 symptoms, genetic polymorphisms and treatment decisions associated with risk of cognitive impairment. The second is the absence of model systems in which to test hypotheses relating infection to cognition. The third is the need for consortia for studying both existing and new longitudinal cohorts in which to monitor long term consequences of COVID-19 infection. A final knowledge gap discussed is the impact of the isolation and lack of social services brought about by quarantine/lockdowns on people living with dementia and their caregivers. Research into these areas may lead to interventions that reduce the overall risk of cognitive decline for COVID-19 survivors.

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Published In

Alzheimers Dement

DOI

EISSN

1552-5279

Publication Date

May 2022

Volume

18

Issue

5

Start / End Page

1038 / 1046

Location

United States

Related Subject Headings

  • Humans
  • Geriatrics
  • Communicable Disease Control
  • Cognitive Dysfunction
  • Caregivers
  • COVID-19
  • Alzheimer Disease
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Gordon, M. N., Heneka, M. T., Le Page, L. M., Limberger, C., Morgan, D., Tenner, A. J., … Willette, S. A. (2022). Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimers Dement, 18(5), 1038–1046. https://doi.org/10.1002/alz.12488
Gordon, Marcia N., Michael T. Heneka, Lydia M. Le Page, Christian Limberger, David Morgan, Andrea J. Tenner, Niccolò Terrando, Auriel A. Willette, and Sara A. Willette. “Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.Alzheimers Dement 18, no. 5 (May 2022): 1038–46. https://doi.org/10.1002/alz.12488.
Gordon MN, Heneka MT, Le Page LM, Limberger C, Morgan D, Tenner AJ, et al. Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimers Dement. 2022 May;18(5):1038–46.
Gordon, Marcia N., et al. “Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.Alzheimers Dement, vol. 18, no. 5, May 2022, pp. 1038–46. Pubmed, doi:10.1002/alz.12488.
Gordon MN, Heneka MT, Le Page LM, Limberger C, Morgan D, Tenner AJ, Terrando N, Willette AA, Willette SA. Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research. Alzheimers Dement. 2022 May;18(5):1038–1046.
Journal cover image

Published In

Alzheimers Dement

DOI

EISSN

1552-5279

Publication Date

May 2022

Volume

18

Issue

5

Start / End Page

1038 / 1046

Location

United States

Related Subject Headings

  • Humans
  • Geriatrics
  • Communicable Disease Control
  • Cognitive Dysfunction
  • Caregivers
  • COVID-19
  • Alzheimer Disease
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences