Primary isolated hepatosplenic sarcoidosis mimicking malignancy and causing symptomatic hypercalcaemia.

Journal Article (Journal Article)

This is a case of a 67-year-old woman, known to have multiple medical problems, mainly papillary thyroid cancer status post-total thyroidectomy and cervical neck dissection in addition to radioactive iodine currently in remission for 1 year, who presented to the hospital with severe weakness and fatigue. The initial workup showed significant hypercalcaemia and suppressed Parathyroid hormone (PTH). The patient was treated with hydration and pamidronate and her hypercalcaemia and symptoms improved. The differential was wide, however, a CT scan of the chest, abdomen and pelvis did show multiple liver and splenic nodular lesions; therefore, malignancy was the highest possible diagnosis. Biopsy of the splenic lesion confirmed the diagnosis of sarcoidosis. Therefore, the patient was diagnosed with primary isolated nodular hepatosplenic sarcoidosis mimicking malignancy and causing significant symptomatic hypercalcaemia.

Full Text

Duke Authors

Cited Authors

  • Haykal, T; Sundus, S; Bachuwa, G; Danish, R

Published Date

  • January 22, 2019

Published In

Volume / Issue

  • 12 / 1

Start / End Page

  • e227703 -

PubMed ID

  • 30674496

Pubmed Central ID

  • PMC6347923

Electronic International Standard Serial Number (EISSN)

  • 1757-790X

International Standard Serial Number (ISSN)

  • 1757-790X

Digital Object Identifier (DOI)

  • 10.1136/bcr-2018-227703

Language

  • eng