When Variants Collide: An Unusual Presentation of Metastatic Gastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm.
Publication
, Journal Article
Deliwala, SS; Ponnapalli, A; Gakhal, I; Modi, V; Haykal, T; Bachuwa, G; Chawla, S
Published in: ACG case reports journal
April 2021
Gastrointestinal neuroendocrine neoplasms were recently reclassified into the 2019 World Health Organization schema into well-differentiated neuroendocrine tumors, poorly differentiated neuroendocrine carcinomas, and mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs). Among these, gastric MiNENs are exceedingly rare and often metastasize quickly without diagnostic clues. We present a refractory gastric MiNEN with unique presenting features. This case highlights the clinical spectrum of these tumors, the importance of accurate histochemical interpretation, and clinical management in the absence of formalized guidelines. Future therapies looking at novel targets and palliative symptom relief are needed.
Duke Scholars
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Published In
ACG case reports journal
DOI
EISSN
2326-3253
ISSN
2326-3253
Publication Date
April 2021
Volume
8
Issue
4
Start / End Page
e00569
Citation
APA
Chicago
ICMJE
MLA
NLM
Deliwala, S. S., Ponnapalli, A., Gakhal, I., Modi, V., Haykal, T., Bachuwa, G., & Chawla, S. (2021). When Variants Collide: An Unusual Presentation of Metastatic Gastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm. ACG Case Reports Journal, 8(4), e00569. https://doi.org/10.14309/crj.0000000000000569
Deliwala, Smit S., Anoosha Ponnapalli, Inderdeep Gakhal, Viraj Modi, Tarek Haykal, Ghassan Bachuwa, and Saurabh Chawla. “When Variants Collide: An Unusual Presentation of Metastatic Gastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm.” ACG Case Reports Journal 8, no. 4 (April 2021): e00569. https://doi.org/10.14309/crj.0000000000000569.
Deliwala SS, Ponnapalli A, Gakhal I, Modi V, Haykal T, Bachuwa G, et al. When Variants Collide: An Unusual Presentation of Metastatic Gastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm. ACG case reports journal. 2021 Apr;8(4):e00569.
Deliwala, Smit S., et al. “When Variants Collide: An Unusual Presentation of Metastatic Gastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm.” ACG Case Reports Journal, vol. 8, no. 4, Apr. 2021, p. e00569. Epmc, doi:10.14309/crj.0000000000000569.
Deliwala SS, Ponnapalli A, Gakhal I, Modi V, Haykal T, Bachuwa G, Chawla S. When Variants Collide: An Unusual Presentation of Metastatic Gastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm. ACG case reports journal. 2021 Apr;8(4):e00569.
Published In
ACG case reports journal
DOI
EISSN
2326-3253
ISSN
2326-3253
Publication Date
April 2021
Volume
8
Issue
4
Start / End Page
e00569