The management of toxicities from immune, targeted and ADCs treatments in patients with urothelial cancer.

Journal Article (Journal Article;Review)

Newly approved systemic treatment options for metastatic urothelial cancer (mUC) have diversified treatments and improved responses and survival for chemotherapy refractory disease. These systemic treatments have associated toxicities which need appropriate management for patients to stay on treatment and potentially have longer benefit from treatment. We review the expected toxicities of immune checkpoint inhibitors, FGFR inhibitors such as erdafitinib, and antibody drug conjugates such as enfortumab vedotin and sacituzumab govitecan.

Full Text

Duke Authors

Cited Authors

  • Atiq, S; Hirshman, N; Shariff, A; Zhang, T

Published Date

  • December 30, 2021

Published In

PubMed ID

  • 34973855

Electronic International Standard Serial Number (EISSN)

  • 1873-2496

Digital Object Identifier (DOI)

  • 10.1016/j.urolonc.2021.10.002

Language

  • eng

Conference Location

  • United States