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Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition.

Publication ,  Journal Article
Rimbach, R; Yamada, Y; Sagayama, H; Ainslie, PN; Anderson, LF; Anderson, LJ; Arab, L; Baddou, I; Bedu-Addo, K; Blaak, EE; Blanc, S; Bonomi, AG ...
Published in: Nat Commun
January 10, 2022
Published version (DOI) Link to item

Low total energy expenditure (TEE, MJ/d) has been a hypothesized risk factor for weight gain, but repeatability of TEE, a critical variable in longitudinal studies of energy balance, is understudied. We examine repeated doubly labeled water (DLW) measurements of TEE in 348 adults and 47 children from the IAEA DLW Database (mean ± SD time interval: 1.9 ± 2.9 y) to assess repeatability of TEE, and to examine if TEE adjusted for age, sex, fat-free mass, and fat mass is associated with changes in weight or body composition. Here, we report that repeatability of TEE is high for adults, but not children. Bivariate Bayesian mixed models show no among or within-individual correlation between body composition (fat mass or percentage) and unadjusted TEE in adults. For adults aged 20-60 y (N = 267; time interval: 7.4 ± 12.2 weeks), increases in adjusted TEE are associated with weight gain but not with changes in body composition; results are similar for subjects with intervals >4 weeks (N = 53; 29.1 ± 12.8 weeks). This suggests low TEE is not a risk factor for, and high TEE is not protective against, weight or body fat gain over the time intervals tested.

Duke Scholars

William Erle Kraus
Author William Erle Kraus Medicine, Cardiology
Herman Pontzer
Author Herman Pontzer Evolutionary Anthropology
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Published In

Nat Commun

DOI

10.1038/s41467-021-27246-z

EISSN

2041-1723

Publication Date

January 10, 2022

Volume

13

Issue

1

Start / End Page

99

Location

England

Related Subject Headings

  • Weight Gain
  • Water
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Isotope Labeling
  • Humans
  • Female
  • Energy Metabolism
  • Databases, Factual
 

Citation

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Rimbach, R., Yamada, Y., Sagayama, H., Ainslie, P. N., Anderson, L. F., Anderson, L. J., … IAEA DLW Database Consortium, . (2022). Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition. Nat Commun, 13(1), 99. https://doi.org/10.1038/s41467-021-27246-z
Rimbach, Rebecca, Yosuke Yamada, Hiroyuki Sagayama, Philip N. Ainslie, Lene F. Anderson, Liam J. Anderson, Lenore Arab, et al. “Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition.” Nat Commun 13, no. 1 (January 10, 2022): 99. https://doi.org/10.1038/s41467-021-27246-z.
Rimbach R, Yamada Y, Sagayama H, Ainslie PN, Anderson LF, Anderson LJ, et al. Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition. Nat Commun. 2022 Jan 10;13(1):99.
Rimbach, Rebecca, et al. “Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition.” Nat Commun, vol. 13, no. 1, Jan. 2022, p. 99. Pubmed, doi:10.1038/s41467-021-27246-z.
Rimbach R, Yamada Y, Sagayama H, Ainslie PN, Anderson LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Bovet P, Buchowski MS, Butte NF, Camps SGJA, Close GL, Cooper JA, Das SK, Dugas LR, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin CK, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl CU, Luke AH, Rood J, Schoeller DA, Westerterp KR, Wong WW, Speakman JR, Pontzer H, IAEA DLW Database Consortium. Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition. Nat Commun. 2022 Jan 10;13(1):99.

Published In

Nat Commun

DOI

10.1038/s41467-021-27246-z

EISSN

2041-1723

Publication Date

January 10, 2022

Volume

13

Issue

1

Start / End Page

99

Location

England

Related Subject Headings

  • Weight Gain
  • Water
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Isotope Labeling
  • Humans
  • Female
  • Energy Metabolism
  • Databases, Factual