Off-label uses of the Pipeline embolization device: a review of the literature.

Journal Article (Journal Article;Review)

The Pipeline embolization device (PED) is the most widely used flow diverter in endovascular neurosurgery. In 2011, the device received FDA approval for the treatment of large and giant aneurysms in the internal carotid artery extending from the petrous to the superior hypophyseal segments. However, as popularity of the device grew and neurosurgeons gained more experience, its use has extended to several other indications. Some of these off-label uses include previously treated aneurysms, acutely ruptured aneurysms, small aneurysms, distal circulation aneurysms, posterior circulation aneurysms, fusiform aneurysms, dissecting aneurysms, pseudoaneurysms, and even carotid-cavernous fistulas. The authors present a literature review of the safety and efficacy of the PED in these off-label uses.

Full Text

Duke Authors

Cited Authors

  • Patel, PD; Chalouhi, N; Atallah, E; Tjoumakaris, S; Hasan, D; Zarzour, H; Rosenwasser, R; Jabbour, P

Published Date

  • June 2017

Published In

Volume / Issue

  • 42 / 6

Start / End Page

  • E4 -

PubMed ID

  • 28565978

Electronic International Standard Serial Number (EISSN)

  • 1092-0684

Digital Object Identifier (DOI)

  • 10.3171/2017.3.FOCUS1742


  • eng

Conference Location

  • United States