In vitro accuracy and inter-observer reliability of CT angiography in detecting intracranial aneurysm enlargement.

Journal Article (Journal Article)

BACKGROUND AND PURPOSE: To evaluate the accuracy and inter-observer variability when CT angiography is used to identify unruptured intracranial aneurysm growth. METHODS: Two silicone phantom models were used in this study. Each phantom had eight aneurysms of variable size. The size and location of aneurysms in phantom 1 were representative of real patient aneurysms who presented to our institution. Phantom 2 contained aneurysms in the same locations, but with enlargement in various directions. Three blinded board-certified neuroradiologists were asked to identify the size of each aneurysm in three dimensions using CT angiography. The individual enlargement detection rates and inter-observer agreement rates of aneurysm enlargement among the three experts were calculated. RESULTS: The detection rate of aneurysm enlargement in one dimension was 58.3% among the three observers. Accurate detection of enlargement in all dimensions was 12.5% among the three observers. Detection accuracy was not related to the size of enlargement. Significant inter-observer measurement variability was present. CONCLUSION: The use of CT angiography was associated with a poor ability to identify aneurysm enlargementaccurately. Further human studies are required to confirm our findings.

Full Text

Duke Authors

Cited Authors

  • Al Kasab, S; Nakagawa, D; Zanaty, M; Bathla, G; Policeni, B; Soni, N; Allan, L; Hudson, J; Limaye, K; Ortega-Gutierrez, S; Samaniego, EA; Hasan, D

Published Date

  • October 2019

Published In

Volume / Issue

  • 11 / 10

Start / End Page

  • 1015 - 1018

PubMed ID

  • 30842308

Electronic International Standard Serial Number (EISSN)

  • 1759-8486

Digital Object Identifier (DOI)

  • 10.1136/neurintsurg-2019-014737


  • eng

Conference Location

  • England