Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections.
Publication
, Journal Article
Lodise, TP; Scheetz, M; Carreno, JJ; Chambers, H; Fowler, V; Holland, TL
Published in: Open Forum Infect Dis
February 2022
Among patients with methicillin-resistant Staphylococcus aureus bacteremia, vancomycin-associated acute kidney injury increased as a function of the day 2 area under the curve (AUC), even for daily AUCs within the recommended therapeutic range (400-600). Further data are needed to determine if daily AUCs <400 can be maintained without compromising efficacy.
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Published In
Open Forum Infect Dis
DOI
ISSN
2328-8957
Publication Date
February 2022
Volume
9
Issue
2
Start / End Page
ofab651
Location
United States
Related Subject Headings
- 3207 Medical microbiology
- 3202 Clinical sciences
Citation
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Chicago
ICMJE
MLA
NLM
Lodise, T. P., Scheetz, M., Carreno, J. J., Chambers, H., Fowler, V., & Holland, T. L. (2022). Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections. Open Forum Infect Dis, 9(2), ofab651. https://doi.org/10.1093/ofid/ofab651
Lodise, Thomas P., Marc Scheetz, Joseph J. Carreno, Henry Chambers, Vance Fowler, and Thomas L. Holland. “Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections.” Open Forum Infect Dis 9, no. 2 (February 2022): ofab651. https://doi.org/10.1093/ofid/ofab651.
Lodise TP, Scheetz M, Carreno JJ, Chambers H, Fowler V, Holland TL. Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections. Open Forum Infect Dis. 2022 Feb;9(2):ofab651.
Lodise, Thomas P., et al. “Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections.” Open Forum Infect Dis, vol. 9, no. 2, Feb. 2022, p. ofab651. Pubmed, doi:10.1093/ofid/ofab651.
Lodise TP, Scheetz M, Carreno JJ, Chambers H, Fowler V, Holland TL. Associations Between Vancomycin Exposure and Acute Kidney Injury Within the Recommended Area Under the Curve Therapeutic Exposure Range Among Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections. Open Forum Infect Dis. 2022 Feb;9(2):ofab651.
Published In
Open Forum Infect Dis
DOI
ISSN
2328-8957
Publication Date
February 2022
Volume
9
Issue
2
Start / End Page
ofab651
Location
United States
Related Subject Headings
- 3207 Medical microbiology
- 3202 Clinical sciences