Auditory cortical activity drives feedback-dependent vocal control in marmosets.

Journal Article (Journal Article)

Vocal communication is a sensory-motor process requiring auditory self-monitoring to correct errors and to ensure accurate vocal production. When presented with altered speech feedback, humans rapidly change their speech to compensate. Although previous evidence has demonstrated suppression of auditory cortex during both speech and animal vocalization, the specific role of auditory cortex in such feedback-dependent control is unknown. Here we show the relationship between neural activity in the auditory cortex and feedback-dependent vocal control in marmoset monkeys. We demonstrate that marmosets, like humans, exhibit feedback control of vocal acoustics. We further show that feedback-sensitive activity of auditory cortex neurons predict such compensatory vocal changes. Finally, we demonstrate that electrical microstimulation of auditory cortex rapidly evokes similar changes in vocal production. These results are evidence for a causal role of auditory cortex in vocal self-monitoring and feedback-dependent control, and have implications for understanding human speech motor control.

Full Text

Duke Authors

Cited Authors

  • Eliades, SJ; Tsunada, J

Published Date

  • June 29, 2018

Published In

Volume / Issue

  • 9 / 1

Start / End Page

  • 2540 -

PubMed ID

  • 29959315

Pubmed Central ID

  • PMC6026141

Electronic International Standard Serial Number (EISSN)

  • 2041-1723

Digital Object Identifier (DOI)

  • 10.1038/s41467-018-04961-8


  • eng

Conference Location

  • England