Wireless multichannel biopotential recording using an integrated FM telemetry circuit.
Journal Article (Journal Article)
This paper presents a four-channel telemetric microsystem featuring on-chip alternating current amplification, direct current baseline stabilization, clock generation, time-division multiplexing, and wireless frequency-modulation transmission of microvolt- and millivolt-range input biopotentials in the very high frequency band of 94-98 MHz over a distance of approximately 0.5 m. It consists of a 4.84-mm2 integrated circuit, fabricated using a 1.5-microm double-poly double-metal n-well standard complementary metal-oxide semiconductor process, interfaced with only three off-chip components on a custom-designed printed-circuit board that measures 1.7 x 1.2 x 0.16 cm3, and weighs 1.1 g including two miniature 1.5-V batteries. We characterize the microsystem performance, operating in a truly wireless fashion in single-channel and multichannel operation modes, via extensive benchtop and in vitro tests in saline utilizing two different micromachined neural recording microelectrodes, while dissipating approximately 2.2 mW from a 3-V power supply. Moreover, we demonstrate successful wireless in vivo recording of spontaneous neural activity at 96.2 MHz from the auditory cortex of an awake marmoset monkey at several transmission distances ranging from 10 to 50 cm with signal-to-noise ratios in the range of 8.4-9.5 dB.
Full Text
Duke Authors
Cited Authors
- Mohseni, P; Najafi, K; Eliades, SJ; Wang, X
Published Date
- September 2005
Published In
Volume / Issue
- 13 / 3
Start / End Page
- 263 - 271
PubMed ID
- 16200750
International Standard Serial Number (ISSN)
- 1534-4320
Digital Object Identifier (DOI)
- 10.1109/TNSRE.2005.853625
Language
- eng
Conference Location
- United States