Disorders of Blood Cell Production in Clinical Oncology

Book Section

Management of hematologic abnormalities in cancer pose tremendous challenges in the care of patients. Clinically significant anemia, thrombocytopenia, and neutropenia can limit the ability to treat the malignancy effectively and can profoundly impact patient morbidity and mortality. These present as manifestations of the malignant process or as acquired sequelae from cancer treatment, such as systemic chemotherapy. In this chapter, we review the pathophysiologic mechanisms and appropriate clinical management of hematologic abnormalities that arise during the care of cancer patients. Therapeutic agents developed to mitigate the complications related to these hematologic abnormalities will also be discussed.

Full Text

Duke Authors

Cited Authors

  • Choe, JH; Crawford, J

Published Date

  • January 1, 2019

Book Title

  • Abeloff’s Clinical Oncology

Start / End Page

  • 514 - 522.e2

International Standard Book Number 13 (ISBN-13)

  • 9780323476744

Digital Object Identifier (DOI)

  • 10.1016/B978-0-323-47674-4.00032-3

Citation Source

  • Scopus