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Effect of commonly used lavage solutions on the polymerization of bone cement.

Publication ,  Journal Article
Wu, M; O'Donnell, J; Cochrane, N; Ryan, S; Belay, E; Myntti, M; Seyler, T
Published in: Orthop Traumatol Surg Res
December 2022

INTRODUCTION: Little is known about the impact irrigation solutions have on the material properties of cement used in hip and knee arthroplasty. We sought to compare the effect of three commonly used lavage solutions on cement polymerization. METHODS: Ten groups were used for cure and mechanical testing: two cement controls, and eight cement groups mixed with test solutions. Test solutions included a commercially available benzalkonium chloride/citric acid solution (BCS), chlorhexidine gluconate (0.05%) (CHG), povidone-iodine 0.35%, and normal saline added at cement mixing onset. Cement dough-time, set-time, and compression testing were performed following The American Society for Testing and Materials guidelines. RESULTS: Povidone-iodine had shorter dough-time (1min 34sec, sd 1min 5sec) versus controls (1min 56sec, sd 1min 35sec), p=0.0419. Cement exposed to all lavage samples had significantly reduced set-time. Compressive strength was reduced for all surgical lavages (p<0.001). Pairwise testing revealed that all lavage treatments reduced offset strength versus controls (p<0.001). CONCLUSION: Bone cement exposed to lavage solutions during the cement mixing-phase showed accelerated set-times and decreased compressive strength. If bone is not dry, and cement has not finished mixing at the time of application, cement curing time may be shortened. Additionally, bone cement should reach dough phase prior to pre-closure surgical lavage. LEVEL OF EVIDENCE: III; case control study.

Duke Scholars

Published In

Orthop Traumatol Surg Res

DOI

EISSN

1877-0568

Publication Date

December 2022

Volume

108

Issue

8

Start / End Page

103243

Location

France

Related Subject Headings

  • Therapeutic Irrigation
  • Povidone-Iodine
  • Polymerization
  • Humans
  • Case-Control Studies
  • Bone Cements
 

Citation

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MLA
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Wu, M., O’Donnell, J., Cochrane, N., Ryan, S., Belay, E., Myntti, M., & Seyler, T. (2022). Effect of commonly used lavage solutions on the polymerization of bone cement. Orthop Traumatol Surg Res, 108(8), 103243. https://doi.org/10.1016/j.otsr.2022.103243
Wu, Mark, Jeffrey O’Donnell, Niall Cochrane, Sean Ryan, Elshaday Belay, Matthew Myntti, and Thorsten Seyler. “Effect of commonly used lavage solutions on the polymerization of bone cement.Orthop Traumatol Surg Res 108, no. 8 (December 2022): 103243. https://doi.org/10.1016/j.otsr.2022.103243.
Wu M, O’Donnell J, Cochrane N, Ryan S, Belay E, Myntti M, et al. Effect of commonly used lavage solutions on the polymerization of bone cement. Orthop Traumatol Surg Res. 2022 Dec;108(8):103243.
Wu, Mark, et al. “Effect of commonly used lavage solutions on the polymerization of bone cement.Orthop Traumatol Surg Res, vol. 108, no. 8, Dec. 2022, p. 103243. Pubmed, doi:10.1016/j.otsr.2022.103243.
Wu M, O’Donnell J, Cochrane N, Ryan S, Belay E, Myntti M, Seyler T. Effect of commonly used lavage solutions on the polymerization of bone cement. Orthop Traumatol Surg Res. 2022 Dec;108(8):103243.
Journal cover image

Published In

Orthop Traumatol Surg Res

DOI

EISSN

1877-0568

Publication Date

December 2022

Volume

108

Issue

8

Start / End Page

103243

Location

France

Related Subject Headings

  • Therapeutic Irrigation
  • Povidone-Iodine
  • Polymerization
  • Humans
  • Case-Control Studies
  • Bone Cements