The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection.
Publication
, Journal Article
Harding, AT; Heaton, NS
Published in: Cancers (Basel)
February 12, 2022
Sex hormones, such as estrogen and testosterone, are steroid compounds with well-characterized effects on the coordination and development of vertebrate reproductive systems. Since their discovery, however, it has become clear that these "sex hormones" also regulate/influence a broad range of biological functions. In this review, we will summarize some current findings on how estrogens interact with and regulate inflammation and immunity. Specifically, we will focus on describing the mechanisms by which estrogens alter immune pathway activation, the impact of these changes during infection and the development of long-term immunity, and how different types of estrogens and their respective concentrations mediate these outcomes.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Cancers (Basel)
DOI
ISSN
2072-6694
Publication Date
February 12, 2022
Volume
14
Issue
4
Location
Switzerland
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Harding, A. T., & Heaton, N. S. (2022). The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection. Cancers (Basel), 14(4). https://doi.org/10.3390/cancers14040909
Harding, Alfred T., and Nicholas S. Heaton. “The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection.” Cancers (Basel) 14, no. 4 (February 12, 2022). https://doi.org/10.3390/cancers14040909.
Harding AT, Heaton NS. The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection. Cancers (Basel). 2022 Feb 12;14(4).
Harding, Alfred T., and Nicholas S. Heaton. “The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection.” Cancers (Basel), vol. 14, no. 4, Feb. 2022. Pubmed, doi:10.3390/cancers14040909.
Harding AT, Heaton NS. The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection. Cancers (Basel). 2022 Feb 12;14(4).
Published In
Cancers (Basel)
DOI
ISSN
2072-6694
Publication Date
February 12, 2022
Volume
14
Issue
4
Location
Switzerland
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis