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Development of a practical clinical application of NIPAM kV-CBCT dosimetry

Publication ,  Conference
Pant, K; Oldham, M; Giles, W; Adamson, J
Published in: Journal of Physics: Conference Series
January 24, 2022

We report our progress towards developing a clinical application of NIPAM kV-CBCT dosimetry. The goal is to develop a practical kV-MV isocenter verification test for which the measurement and analysis can be carried out quickly (within an hour), and that eliminates the need for separate readout (other than on board kV-CBCT) or extra analysis steps such as image registration. Isocenter verification is performed using a NIPAM 3D gel dosimeter which is irradiated with a small field to ~16Gy at eight unique couch/gantry angles. Pre- and post-irradiation kV-CBCT images are acquired and dose is manifest as the intensity difference between pre- and post-CBCTs due to radiation induced changes in density. Code was developed to detect the geometry of each beam in the kV-CBCT and quantify relevant parameters. We applied this technique to verify the isocenter for MLCs as well as for SRS cones. The measured radius to encompass all beams for 4mm, 6mm, 7.5mm, 12.5mm, and 15mm cones was 0.55±0.11mm. The efficiency, robustness to setup errors, and unique ability to visualize spatial uncertainties in the kV-CBCT coordinate system make the NIPAM kV-CBCT test a practical and unique tool for kV-MV isocenter verification.

Duke Scholars

Published In

Journal of Physics: Conference Series

DOI

EISSN

1742-6596

ISSN

1742-6588

Publication Date

January 24, 2022

Volume

2167

Issue

1

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

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Pant, K., Oldham, M., Giles, W., & Adamson, J. (2022). Development of a practical clinical application of NIPAM kV-CBCT dosimetry. In Journal of Physics: Conference Series (Vol. 2167). https://doi.org/10.1088/1742-6596/2167/1/012007
Pant, K., M. Oldham, W. Giles, and J. Adamson. “Development of a practical clinical application of NIPAM kV-CBCT dosimetry.” In Journal of Physics: Conference Series, Vol. 2167, 2022. https://doi.org/10.1088/1742-6596/2167/1/012007.
Pant K, Oldham M, Giles W, Adamson J. Development of a practical clinical application of NIPAM kV-CBCT dosimetry. In: Journal of Physics: Conference Series. 2022.
Pant, K., et al. “Development of a practical clinical application of NIPAM kV-CBCT dosimetry.” Journal of Physics: Conference Series, vol. 2167, no. 1, 2022. Scopus, doi:10.1088/1742-6596/2167/1/012007.
Pant K, Oldham M, Giles W, Adamson J. Development of a practical clinical application of NIPAM kV-CBCT dosimetry. Journal of Physics: Conference Series. 2022.
Journal cover image

Published In

Journal of Physics: Conference Series

DOI

EISSN

1742-6596

ISSN

1742-6588

Publication Date

January 24, 2022

Volume

2167

Issue

1

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics