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Meta-analytic activation maps can help identify affective processes captured by contrast-based task fMRI: the case of threat-related facial expressions.

Publication ,  Journal Article
Kim, MJ; Knodt, AR; Hariri, AR
Published in: Social cognitive and affective neuroscience
September 2022

Meta-analysis of functional magnetic resonance imaging (fMRI) data is an effective method for capturing the distributed patterns of brain activity supporting discrete cognitive and affective processes. One opportunity presented by the resulting meta-analysis maps (MAMs) is as a reference for better understanding the nature of individual contrast maps (ICMs) derived from specific task fMRI data. Here, we compared MAMs from 148 neuroimaging studies representing emotion categories of fear, anger, disgust, happiness and sadness with ICMs from fearful > neutral and angry > neutral faces from an independent dataset of task fMRI (n = 1263). Analyses revealed that both fear and anger ICMs exhibited the greatest pattern similarity to fear MAMs. As the number of voxels included for the computation of pattern similarity became more selective, the specificity of MAM-ICM correspondence decreased. Notably, amygdala activity long considered critical for processing threat-related facial expressions was neither sufficient nor necessary for detecting MAM-ICM pattern similarity effects. Our analyses suggest that both fearful and angry facial expressions are best captured by distributed patterns of brain activity, a putative neural correlate of threat. More generally, our analyses demonstrate how MAMs can be leveraged to better understand affective processes captured by ICMs in task fMRI data.

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Published In

Social cognitive and affective neuroscience

DOI

EISSN

1749-5024

ISSN

1749-5016

Publication Date

September 2022

Volume

17

Issue

9

Start / End Page

777 / 787

Related Subject Headings

  • Magnetic Resonance Imaging
  • Humans
  • Facial Expression
  • Experimental Psychology
  • Emotions
  • Anger
  • Amygdala
  • 5203 Clinical and health psychology
  • 5202 Biological psychology
  • 3209 Neurosciences
 

Citation

APA
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Kim, M. J., Knodt, A. R., & Hariri, A. R. (2022). Meta-analytic activation maps can help identify affective processes captured by contrast-based task fMRI: the case of threat-related facial expressions. Social Cognitive and Affective Neuroscience, 17(9), 777–787. https://doi.org/10.1093/scan/nsac010
Kim, M Justin, Annchen R. Knodt, and Ahmad R. Hariri. “Meta-analytic activation maps can help identify affective processes captured by contrast-based task fMRI: the case of threat-related facial expressions.Social Cognitive and Affective Neuroscience 17, no. 9 (September 2022): 777–87. https://doi.org/10.1093/scan/nsac010.
Kim, M. Justin, et al. “Meta-analytic activation maps can help identify affective processes captured by contrast-based task fMRI: the case of threat-related facial expressions.Social Cognitive and Affective Neuroscience, vol. 17, no. 9, Sept. 2022, pp. 777–87. Epmc, doi:10.1093/scan/nsac010.
Journal cover image

Published In

Social cognitive and affective neuroscience

DOI

EISSN

1749-5024

ISSN

1749-5016

Publication Date

September 2022

Volume

17

Issue

9

Start / End Page

777 / 787

Related Subject Headings

  • Magnetic Resonance Imaging
  • Humans
  • Facial Expression
  • Experimental Psychology
  • Emotions
  • Anger
  • Amygdala
  • 5203 Clinical and health psychology
  • 5202 Biological psychology
  • 3209 Neurosciences