An MKP-MAPK protein phosphorylation cascade controls vascular immunity in plants.

Journal Article (Journal Article)

Global crop production is greatly reduced by vascular diseases. These diseases include bacterial blight of rice and crucifer black rot caused by Xanthomonas oryzae pv. oryzae (Xoo ) and Xanthomonas campestris pv. campestris (Xcc ). The molecular mechanisms that activate vascular defense against such pathogens remains underexplored. Here, we show that an Arabidopsis MAPK phosphatase 1 (MKP1) mutant has increased host susceptibility to the adapted pathogen Xcc and is compromised in nonhost resistance to the rice pathogen Xoo . MKP1 regulates MAPK-mediated phosphorylation of the transcription factor MYB4 that negatively regulates vascular lignification through inhibiting lignin biosynthesis. Induction of lignin biosynthesis is, therefore, an important part of vascular-specific immunity. The role of MKP-MAPK-MYB signaling in lignin biosynthesis and vascular resistance to Xoo is conserved in rice, indicating that these factors form a tissue-specific defense regulatory network. Our study likely reveals a major vascular immune mechanism that underlies tissue-specific disease resistance against bacterial pathogens in plants.

Full Text

Duke Authors

Cited Authors

  • Lin, H; Wang, M; Chen, Y; Nomura, K; Hui, S; Gui, J; Zhang, X; Wu, Y; Liu, J; Li, Q; Deng, Y; Li, L; Yuan, M; Wang, S; He, SY; He, Z

Published Date

  • March 9, 2022

Published In

Volume / Issue

  • 8 / 10

Start / End Page

  • eabg8723 -

PubMed ID

  • 35263144

Pubmed Central ID

  • PMC8906744

Electronic International Standard Serial Number (EISSN)

  • 2375-2548

International Standard Serial Number (ISSN)

  • 2375-2548

Digital Object Identifier (DOI)

  • 10.1126/sciadv.abg8723

Language

  • eng