A comparison of alternative assessments of depressive symptom severity: a pilot study.

Journal Article (Journal Article;Multicenter Study)

This study compared the performance of an itemized symptom self-report (Inventory of Depressive Symptomatology - Self-Report; IDS-SR), patient global ratings, and clinician global ratings with an itemized clinician-rated symptom severity measure (Inventory of Depressive Symptomatology - Clinician-Rated; IDS-C) in detecting treatment effects in patients with major depressive disorder (MDD). A total of 28 inpatients (30.8% psychotic) and 34 outpatients (17.9% psychotic) with MDD began treatment that followed the Texas medication algorithm. The clinicians completed the IDS-C and a Physician Global Rating Scale (PhGRS) at each assessment visit, while the patients completed the IDS-SR and a Patient Global Rating Scale (PtGRS). Change scores from the baseline to subsequent weeks were computed for all subjects, utilizing all four measures. The IDS-SR was a significant independent predictor of the response to treatment as compared to the two global ratings. The IDS-SR was as sensitive to change as the IDS-C. While the clinician-rated itemized symptom severity rating scale remains the standard to assess the symptomatic outcome of the treatment of MDD, a self-report of identical symptomatology may be a reasonable alternative for many patients.

Full Text

Duke Authors

Cited Authors

  • Biggs, MM; Shores-Wilson, K; Rush, AJ; Carmody, TJ; Trivedi, MH; Crismon, ML; Toprac, MG; Mason, M

Published Date

  • November 20, 2000

Published In

Volume / Issue

  • 96 / 3

Start / End Page

  • 269 - 279

PubMed ID

  • 11084222

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/s0165-1781(00)00235-3


  • eng

Conference Location

  • Ireland