Advances and challenges in programming pattern formation using living cells.

Journal Article (Review;Journal Article)

Spatial patterning of cell populations is a ubiquitous phenomenon in nature. Patterns occur at various length and time scales and exhibit immense diversity. In addition to offering a deeper understanding of the emergence of patterns in nature, the ability to program synthetic patterns using living cells has the potential for broad applications. To date, however, progress in engineering pattern formation has been hampered by technical challenges. In this Review, we discuss recent advances in programming pattern formation in terms of biological insights, experimental and computational tool development, and potential applications.

Full Text

Duke Authors

Cited Authors

  • Lu, J; Şimşek, E; Silver, A; You, L

Published Date

  • June 2022

Published In

Volume / Issue

  • 68 /

Start / End Page

  • 102147 -

PubMed ID

  • 35472832

Pubmed Central ID

  • PMC9158282

Electronic International Standard Serial Number (EISSN)

  • 1879-0402

International Standard Serial Number (ISSN)

  • 1367-5931

Digital Object Identifier (DOI)

  • 10.1016/j.cbpa.2022.102147


  • eng