Laser-Assisted Delivery of Topical Cidofovir in the Treatment of Plantar Warts.
Journal Article (Journal Article)
Recalcitrant plantar warts pose a therapeutic challenge. Cidofovir is a viral DNA polymerase inhibitor that has been used in treatment of verrucae with greater success than traditional treatments in some cases. Laser-assisted drug delivery enhances drug penetration beyond the epidermis and is particularly well-suited, though under-utilized, to target palmoplantar verrucae. We report the use of an erbium:yttrium-aluminum-garnet (Er:YAG) ablative fractional laser (AFL) followed by topical cidofovir in treating recalcitrant plantar warts. Two patients were treated with a 2940-nm Er:YAG laser at depths of 1.2-1.5 mm followed by topical application of cidofovir 75 mg/mL. Both patients exhibited a significant reduction in lesion size and improvement in symptoms. AFL-assisted delivery of topical cidofovir represents a promising therapeutic option for recalcitrant plantar warts. J Drugs Dermatol. 2019;18(7):663-665.
Full Text
Duke Authors
Cited Authors
- Coates, M; Patel, J; Powers, C; Burton, C
Published Date
- July 1, 2019
Published In
Volume / Issue
- 18 / 7
Start / End Page
- 663 - 665
PubMed ID
- 31334626
International Standard Serial Number (ISSN)
- 1545-9616
Language
- eng
Conference Location
- United States