Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.
Journal Article (Letter;Multicenter Study)
A polygenic risk score (PGS) is associated with obstructive coronary artery disease (CAD) independent of traditional risk factors. Coronary computed tomography angiography (CTA) can characterize coronary plaques, including features of highrisk CAD. However, it is unknown if a PGS is associated with obstructive CAD and high-risk CAD phenotypes in patients with symptoms suggestive of CAD.
- Newman, JD; Douglas, PS; Zhbannikov, I; Ferencik, M; Foldyna, B; Hoffmann, U; Shah, SH; Ginsburg, GS; Lu, MT; Voora, D
- October 2022
Volume / Issue
- 252 /
Start / End Page
- 12 - 15
Pubmed Central ID
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)
- United States