An investigation on Michaelis - Menten kinetics based complex dynamics of tumor - immune interaction

Journal Article (Journal Article)

We investigate the dynamics of a three-dimensional tumor-immune interactions system. Local dynamics of the system has studied by the finding stability and Hopf bifurcation at biologically feasible equilibria. Further, chaotic phenomena have been investigated by measuring the asymptotic growth of the corresponding phase space trajectory with the various bifurcating parameters of the system. A dynamics of mean fluctuations of the tumor growth based on its local maxima have investigated under the same parameters. A significant correlation between the fluctuations and the tumor dynamics have verified by statistical analysis.

Full Text

Duke Authors

Cited Authors

  • Das, P; Mukherjee, S

Published Date

  • November 1, 2019

Published In

Volume / Issue

  • 128 /

Start / End Page

  • 297 - 305

International Standard Serial Number (ISSN)

  • 0960-0779

Digital Object Identifier (DOI)

  • 10.1016/j.chaos.2019.08.006

Citation Source

  • Scopus