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A new and efficient synthesis of pyrazole-fused isocoumarins on the solid surface of magnetically separable Fe3O4@SiO2-SO3H nanoparticles

Publication ,  Journal Article
Mukherjee, S; Kundu, A; Pramanik, A
Published in: Tetrahedron Letters
May 11, 2016

A new and efficient procedure has been developed for the synthesis of a series of pyrazole-fused isocoumarins from easily available ninhydrin and arylhydrazones. In this synthesis the condensations of ninhydrin and arylhydrazones are carried out under solvent free conditions employing magnetically separable Fe3O4@SiO2-SO3H nanoparticles as solid acid support. Some members of pyrazole-fused isocoumarins are known to bind to a GABA receptor.

Duke Scholars

Published In

Tetrahedron Letters

DOI

EISSN

1873-3581

ISSN

0040-4039

Publication Date

May 11, 2016

Volume

57

Issue

19

Start / End Page

2103 / 2108

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Mukherjee, S., Kundu, A., & Pramanik, A. (2016). A new and efficient synthesis of pyrazole-fused isocoumarins on the solid surface of magnetically separable Fe3O4@SiO2-SO3H nanoparticles. Tetrahedron Letters, 57(19), 2103–2108. https://doi.org/10.1016/j.tetlet.2016.04.002
Mukherjee, S., A. Kundu, and A. Pramanik. “A new and efficient synthesis of pyrazole-fused isocoumarins on the solid surface of magnetically separable Fe3O4@SiO2-SO3H nanoparticles.” Tetrahedron Letters 57, no. 19 (May 11, 2016): 2103–8. https://doi.org/10.1016/j.tetlet.2016.04.002.
Mukherjee, S., et al. “A new and efficient synthesis of pyrazole-fused isocoumarins on the solid surface of magnetically separable Fe3O4@SiO2-SO3H nanoparticles.” Tetrahedron Letters, vol. 57, no. 19, May 2016, pp. 2103–08. Scopus, doi:10.1016/j.tetlet.2016.04.002.
Journal cover image

Published In

Tetrahedron Letters

DOI

EISSN

1873-3581

ISSN

0040-4039

Publication Date

May 11, 2016

Volume

57

Issue

19

Start / End Page

2103 / 2108

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry