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Nutrition and skin ulcers.

Publication ,  Journal Article
Little, MO
Published in: Curr Opin Clin Nutr Metab Care
January 2013

PURPOSE OF REVIEW: Skin ulcerations cause significant morbidity and mortality, while driving up healthcare utilization and costs. Interventions to prevent ulcers and improve wound healing times are needed to reduce the burden on patients and healthcare systems. It has been well established that weight loss, protein-calorie malnutrition, and dehydration are risk factors for pressure ulcers. Many nutritional interventions have been studied, with studies being of variable quality and producing mixed results. This review aims to clarify the current evidence and highlights the recent advances in the area of nutrition for the prevention and management of skin ulceration. RECENT FINDINGS: Markers for assessing nutritional status will be reviewed first, followed by a discussion on the theoretical benefit of various nutritional interventions on wound healing. Recommendations for nutrient repletion are also included. Finally, the most recent or important literature will be highlighted and the risks and benefits of supplementation are debated. There is mixed evidence for most nutritional interventions, with most studies being of poor quality with variable study designs, lack of control groups, small sample sizes, and short study lengths. SUMMARY: Long-term randomized trials of individual nutrients and clinically relevant endpoints are needed to definitively show the benefit of additional nutritional supplementation over dietary interventions. Until those studies become available, best evidence suggests the importance of screening for malnutrition, calculating resting energy expenditure and caloric needs, and monitoring dietary intake of essential nutrients.

Duke Scholars

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Published In

Curr Opin Clin Nutr Metab Care

DOI

EISSN

1473-6519

Publication Date

January 2013

Volume

16

Issue

1

Start / End Page

39 / 49

Location

England

Related Subject Headings

  • Wound Healing
  • Risk Factors
  • Protein-Energy Malnutrition
  • Pressure Ulcer
  • Nutritional Status
  • Nutrition Assessment
  • Nutrition & Dietetics
  • Micronutrients
  • Humans
  • Energy Metabolism
 

Citation

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Little, M. O. (2013). Nutrition and skin ulcers. Curr Opin Clin Nutr Metab Care, 16(1), 39–49. https://doi.org/10.1097/MCO.0b013e32835bc0a1
Little, Milta O. “Nutrition and skin ulcers.Curr Opin Clin Nutr Metab Care 16, no. 1 (January 2013): 39–49. https://doi.org/10.1097/MCO.0b013e32835bc0a1.
Little MO. Nutrition and skin ulcers. Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):39–49.
Little, Milta O. “Nutrition and skin ulcers.Curr Opin Clin Nutr Metab Care, vol. 16, no. 1, Jan. 2013, pp. 39–49. Pubmed, doi:10.1097/MCO.0b013e32835bc0a1.
Little MO. Nutrition and skin ulcers. Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):39–49.

Published In

Curr Opin Clin Nutr Metab Care

DOI

EISSN

1473-6519

Publication Date

January 2013

Volume

16

Issue

1

Start / End Page

39 / 49

Location

England

Related Subject Headings

  • Wound Healing
  • Risk Factors
  • Protein-Energy Malnutrition
  • Pressure Ulcer
  • Nutritional Status
  • Nutrition Assessment
  • Nutrition & Dietetics
  • Micronutrients
  • Humans
  • Energy Metabolism