NICE clinical guideline (CG152): the management of Crohn's disease in adults, children and young people.

Journal Article (Journal Article)

BACKGROUND: The guideline offers best practice advice on the care of adults, children and young people with Crohn's disease. AIM: To provide clinically effective and cost-effective evidence-based recommendations to guide clinical practice in a clinical guideline commissioned by the National Institute for Health and Clinical Excellence (NICE). METHODS: A systematic review of the evidence including critical appraisal, meta-analysis and cost-effectiveness modelling. RESULTS: Thirty-one evidence-based recommendations covering induction and maintenance therapy are available. Five key priorities for implementation are identified together with nine future research recommendations. Three guideline versions are available: short (containing just the recommendations), full (containing the full evidence base) and an Understanding NICE guidance for patients and carers. Algorithms have been produced together with a NICE pathway and implementation tools. CONCLUSION: These are the first evidence-based clinical and cost-effectiveness guidelines for Crohn's disease in the United Kingdom.

Full Text

Duke Authors

Cited Authors

  • Mayberry, JF; Lobo, A; Ford, AC; Thomas, A

Published Date

  • January 2013

Published In

Volume / Issue

  • 37 / 2

Start / End Page

  • 195 - 203

PubMed ID

  • 23151246

Electronic International Standard Serial Number (EISSN)

  • 1365-2036

Digital Object Identifier (DOI)

  • 10.1111/apt.12102


  • eng

Conference Location

  • England