OBJECTIVE: To compare academic and demographic metrics among recipients of three major early career radiology, interventional radiology, and radiation oncology grants to National Institutes of Health (NIH) K awardees at the time the grants were awarded and then over the course of their careers. METHODS: Radiologists who received the RSNA Research Scholar Grant, General Electric Radiology Research Academic Fellowship (GERRAF), American Roentgen Ray Society (ARRS) Scholar Award, or NIH Career Development (K) Award before January 1, 2015, were included. Research metrics at the time of grant award (eg, publications) and subsequent scholarly productivity (eg, academic rank, h-index, NIH funding) were recorded until April 2020. Wilcoxon ranked-sum, χ2, logistic regression, and standard least-square regression were used for data analysis. RESULTS: There were 279 recipients: 48 K Award, 115 RSNA Research Scholar Grant, 36 ARRS, and 80 GERRAF. At the time of grant awarding, GERRAF recipients were less likely to have an MD-PhD degree (odds ratio [OR]: 0.36; P = .002) and were more likely to be women (OR: 1.55; P = .042) than K Award recipients. Similarly, recipients of the ARRS (OR: 2.87; P = .010) and GERRAF (OR: 3.19; P = .002) were more likely to have a master's degree. Academic rank, leadership positions, and R01 funding were significant predictors of h-index and total publications over time. Academic rank and the GERRAF were significant predictors of subsequent NIH funding duration but there were no significant predictors of NIH funding amount. CONCLUSIONS: Early career radiology awards, specifically the GERRAF, provide support for female and non-PhD investigators and result in comparable academic performance metrics to NIH K Award recipients.