Corneal hysteresis: ready for prime time?

Journal Article (Review;Journal Article)

Purpose of the review

This review summarizes recent findings on corneal hysteresis, a biomechanical property of the cornea. Corneal hysteresis measurements can be easily acquired clinically and may serve as surrogate markers for biomechanical properties of tissues in the back of the eye, like the lamina cribrosa and peripapillary sclera, which may be related to the susceptibility to glaucomatous damage.

Recent findings

Several studies have provided evidence of the associations between corneal hysteresis and clinically relevant outcomes in glaucoma. Corneal hysteresis has been shown to be predictive of glaucoma development in eyes suspected of having the disease. For eyes already diagnosed with glaucoma, lower corneal hysteresis has been associated with higher risk of progression and faster rates of visual field loss over time. Such associations appear to be stronger than those for corneal thickness, suggesting that corneal hysteresis may be a more important predictive factor. Recent evidence has also shown that cornealcorrected intraocular pressure measurements may present advantages compared to conventional Goldmann tonometry in predicting clinically relevant outcomes in glaucoma.


Given the evidence supporting corneal hysteresis as an important risk factor for glaucoma development and its progression, practitioners should consider measuring corneal hysteresis in all patients at risk for glaucoma, as well as in those already diagnosed with the disease.

Full Text

Duke Authors

Cited Authors

  • Jammal, AA; Medeiros, FA

Published Date

  • May 2022

Published In

Volume / Issue

  • 33 / 3

Start / End Page

  • 243 - 249

PubMed ID

  • 35190508

Electronic International Standard Serial Number (EISSN)

  • 1531-7021

International Standard Serial Number (ISSN)

  • 1040-8738

Digital Object Identifier (DOI)

  • 10.1097/icu.0000000000000842


  • eng