Clin-Star corner: What's new at the interface of geriatrics, infectious diseases, and antimicrobial stewardship.

Journal Article (Journal Article)

Antibiotics are among the leading causes of adverse drug events in older adults. Short-course antibiotic therapy has been shown to work as well as the traditional longer durations for many types of infections. Antibiotic stewardship interventions including deprescribing strategies have shown a reduction in patient readmissions and mortality among older adults. We identified practice-changing clinical trials focusing on three major domains of overprescribing antibiotics in older adults - community-acquired pneumonia, urinary tract infections, and gram-negative bacteremia. The selected articles underscore the safety and effectiveness of shorter durations of antibiotic treatment for infections in older adults, thus highlighting an opportunity for deprescribing in the aging population. By optimizing antibiotic use, we stand to reduce adverse events and enhance overall health outcomes in older adults.

Full Text

Duke Authors

Cited Authors

  • Advani, SD; Schmader, KE; Mody, L

Published Date

  • August 2022

Published In

Volume / Issue

  • 70 / 8

Start / End Page

  • 2214 - 2218

PubMed ID

  • 35704918

Pubmed Central ID

  • PMC9378540

Electronic International Standard Serial Number (EISSN)

  • 1532-5415

Digital Object Identifier (DOI)

  • 10.1111/jgs.17907


  • eng

Conference Location

  • United States