British Society of Gastroenterology guidelines on the management of functional dyspepsia.
Functional dyspepsia (FD) is a common disorder of gut-brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline for the management of dyspepsia was published in 1996. In the interim, substantial advances have been made in understanding the complex pathophysiology of FD, and there has been a considerable amount of new evidence published concerning its diagnosis and classification, with the advent of the Rome IV criteria, and management. The primary aim of this guideline, commissioned by the BSG, is to review and summarise the current evidence to inform and guide clinical practice, by providing a practical framework for evidence-based diagnosis and treatment of patients. The approach to investigating the patient presenting with dyspepsia is discussed, and efficacy of drugs in FD summarised based on evidence derived from a comprehensive search of the medical literature, which was used to inform an update of a series of pairwise and network meta-analyses. Specific recommendations have been made according to the Grading of Recommendations Assessment, Development and Evaluation system. These provide both the strength of the recommendations and the overall quality of evidence. Finally, in this guideline, we consider novel treatments that are in development, as well as highlighting areas of unmet need and priorities for future research.
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- United Kingdom
- Societies, Medical
- Humans
- Gastroenterology & Hepatology
- Gastroenterology
- Dyspepsia
- 3210 Nutrition and dietetics
- 3202 Clinical sciences
- 1114 Paediatrics and Reproductive Medicine
- 1103 Clinical Sciences
Citation
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- United Kingdom
- Societies, Medical
- Humans
- Gastroenterology & Hepatology
- Gastroenterology
- Dyspepsia
- 3210 Nutrition and dietetics
- 3202 Clinical sciences
- 1114 Paediatrics and Reproductive Medicine
- 1103 Clinical Sciences