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Bioinformatics tools for cancer metabolomics

Publication ,  Journal Article
Blekherman, G; Laubenbacher, R; Cortes, DF; Mendes, P; Torti, FM; Akman, S; Torti, SV; Shulaev, V
Published in: Metabolomics
September 1, 2011

It is well known that significant metabolic change take place as cells are transformed from normal to malignant. This review focuses on the use of different bioinformatics tools in cancer metabolomics studies. The article begins by describing different metabolomics technologies and data generation techniques. Overview of the data pre-processing techniques is provided and multivariate data analysis techniques are discussed and illustrated with case studies, including principal component analysis, clustering techniques, self-organizing maps, partial least squares, and discriminant function analysis. Also included is a discussion of available software packages. © 2011 The Author(s).

Published In

Metabolomics

DOI

EISSN

1573-3890

ISSN

1573-3882

Publication Date

September 1, 2011

Volume

7

Issue

3

Start / End Page

329 / 343

Related Subject Headings

  • Analytical Chemistry
  • 3401 Analytical chemistry
  • 3205 Medical biochemistry and metabolomics
  • 3101 Biochemistry and cell biology
  • 1103 Clinical Sciences
  • 0601 Biochemistry and Cell Biology
  • 0301 Analytical Chemistry
 

Citation

APA
Chicago
ICMJE
MLA
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Blekherman, G., Laubenbacher, R., Cortes, D. F., Mendes, P., Torti, F. M., Akman, S., … Shulaev, V. (2011). Bioinformatics tools for cancer metabolomics. Metabolomics, 7(3), 329–343. https://doi.org/10.1007/s11306-010-0270-3
Blekherman, G., R. Laubenbacher, D. F. Cortes, P. Mendes, F. M. Torti, S. Akman, S. V. Torti, and V. Shulaev. “Bioinformatics tools for cancer metabolomics.” Metabolomics 7, no. 3 (September 1, 2011): 329–43. https://doi.org/10.1007/s11306-010-0270-3.
Blekherman G, Laubenbacher R, Cortes DF, Mendes P, Torti FM, Akman S, et al. Bioinformatics tools for cancer metabolomics. Metabolomics. 2011 Sep 1;7(3):329–43.
Blekherman, G., et al. “Bioinformatics tools for cancer metabolomics.” Metabolomics, vol. 7, no. 3, Sept. 2011, pp. 329–43. Scopus, doi:10.1007/s11306-010-0270-3.
Blekherman G, Laubenbacher R, Cortes DF, Mendes P, Torti FM, Akman S, Torti SV, Shulaev V. Bioinformatics tools for cancer metabolomics. Metabolomics. 2011 Sep 1;7(3):329–343.
Journal cover image

Published In

Metabolomics

DOI

EISSN

1573-3890

ISSN

1573-3882

Publication Date

September 1, 2011

Volume

7

Issue

3

Start / End Page

329 / 343

Related Subject Headings

  • Analytical Chemistry
  • 3401 Analytical chemistry
  • 3205 Medical biochemistry and metabolomics
  • 3101 Biochemistry and cell biology
  • 1103 Clinical Sciences
  • 0601 Biochemistry and Cell Biology
  • 0301 Analytical Chemistry