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Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.

Publication ,  Journal Article
Rawal, RB; Farzal, Z; Federspiel, JJ; Sreenath, SB; Thorp, BD; Zanation, AM
Published in: Otolaryngol Head Neck Surg
September 2016

OBJECTIVES: The use of endoscopic approaches for sinonasal malignancy resection has increased, but survival data are limited secondary to disease rarity and new surgical technique. Here we present a systematic review and meta-analysis of endoscopic endonasal resection of sinonasal malignancy. DATA SOURCES: MEDLINE, PubMed Central, NCBI Bookshelf, Cochrane Library, clinicaltrials.gov, National Guideline Clearinghouse. REVIEW METHODS: PRISMA/MOOSE guidelines were followed. MeSH terms were "endoscopic" AND ("esthesioneuroblastoma" OR "sinonasal adenocarcinoma" OR "squamous cell carcinoma" OR "sinonasal undifferentiated carcinoma"). For studies in which individual-level data were available, results were obtained by direct pooling. For studies in which only summary Kaplan-Meier curves were available, numerical data were extracted, traced, and aggregated by fitting a Weibull model. RESULTS: Of 320 studies identified, 35 case series were included (n = 952 patients), with 15 studies analyzed via aggregate modeling and 20 studies analyzed via direct pooling. Two- and 5-year survival rates for patients in aggregate modeling were 87.5% and 72.3%, respectively (mean follow-up: 32.9 months). Two- and 5-year survival for patients in direct pooling were 85.8% and 83.5%, respectively (mean follow-up: 43.0 ± 19.5 months). Significant overall survival difference was found between low- and high-grade cancers (P = .015) but not between low- and high-stage cancers (P = .79). CONCLUSION: Overall 2- and 5-year survival rates are comparable and sometimes greater than those from open craniofacial resection. Survival rates significantly differ by cancer grade but not stage. Journals and investigators should be encouraged to publish retrospective and prospective case series with staged survival updates based on established guidelines.

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Published In

Otolaryngol Head Neck Surg

DOI

EISSN

1097-6817

Publication Date

September 2016

Volume

155

Issue

3

Start / End Page

376 / 386

Location

England

Related Subject Headings

  • Survival Rate
  • Paranasal Sinus Neoplasms
  • Otorhinolaryngology
  • Humans
  • Endoscopy
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Rawal, R. B., Farzal, Z., Federspiel, J. J., Sreenath, S. B., Thorp, B. D., & Zanation, A. M. (2016). Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg, 155(3), 376–386. https://doi.org/10.1177/0194599816646968
Rawal, Rounak B., Zainab Farzal, Jerome J. Federspiel, Satyan B. Sreenath, Brian D. Thorp, and Adam M. Zanation. “Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.Otolaryngol Head Neck Surg 155, no. 3 (September 2016): 376–86. https://doi.org/10.1177/0194599816646968.
Rawal RB, Farzal Z, Federspiel JJ, Sreenath SB, Thorp BD, Zanation AM. Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2016 Sep;155(3):376–86.
Rawal, Rounak B., et al. “Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.Otolaryngol Head Neck Surg, vol. 155, no. 3, Sept. 2016, pp. 376–86. Pubmed, doi:10.1177/0194599816646968.
Rawal RB, Farzal Z, Federspiel JJ, Sreenath SB, Thorp BD, Zanation AM. Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2016 Sep;155(3):376–386.
Journal cover image

Published In

Otolaryngol Head Neck Surg

DOI

EISSN

1097-6817

Publication Date

September 2016

Volume

155

Issue

3

Start / End Page

376 / 386

Location

England

Related Subject Headings

  • Survival Rate
  • Paranasal Sinus Neoplasms
  • Otorhinolaryngology
  • Humans
  • Endoscopy
  • 3202 Clinical sciences
  • 1103 Clinical Sciences