Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide.
Publication
, Journal Article
Feng, Y; Phipps, MD; Phelps, TE; Okoye, NC; Baumeister, JE; Wycoff, DE; Dorman, EF; Wooten, AL; Vlasenko, V; Berendzen, AF; Wilbur, DS ...
Published in: Appl Radiat Isot
January 2019
Positron-emitting 72As is the PET imaging counterpart for beta-emitting 77As. Its parent, no carrier added (n.c.a.) 72Se, was produced for a 72Se/72As generator by irradiating an enriched 7°Ge metal-graphite target via the 70Ge(α, 2 n)72Se reaction. Target dissolution used a fast, environmentally friendly method with 93% radioactivity recovery. Chromatographic parameters of the 72Se/72As generator were evaluated, the eluted n.c.a. 72As was characterized with a phantom imaging study, and the previously reported trithiol and aryl-dithiol ligand systems were radiolabeled with the separated n.c.a. 72As in high yield.
Duke Scholars
Published In
Appl Radiat Isot
DOI
EISSN
1872-9800
Publication Date
January 2019
Volume
143
Start / End Page
113 / 122
Location
England
Related Subject Headings
- Selenium Radioisotopes
- Radiopharmaceuticals
- Radionuclide Generators
- Radioligand Assay
- Radioisotopes
- Positron-Emission Tomography
- Phantoms, Imaging
- Nuclear Medicine & Medical Imaging
- Isotopes
- Humans
Citation
APA
Chicago
ICMJE
MLA
NLM
Feng, Y., Phipps, M. D., Phelps, T. E., Okoye, N. C., Baumeister, J. E., Wycoff, D. E., … Jurisson, S. S. (2019). Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide. Appl Radiat Isot, 143, 113–122. https://doi.org/10.1016/j.apradiso.2018.10.026
Feng, Yutian, Michael D. Phipps, Tim E. Phelps, Nkemakonam C. Okoye, Jakob E. Baumeister, Donald E. Wycoff, Eric F. Dorman, et al. “Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide.” Appl Radiat Isot 143 (January 2019): 113–22. https://doi.org/10.1016/j.apradiso.2018.10.026.
Feng Y, Phipps MD, Phelps TE, Okoye NC, Baumeister JE, Wycoff DE, et al. Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide. Appl Radiat Isot. 2019 Jan;143:113–22.
Feng, Yutian, et al. “Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide.” Appl Radiat Isot, vol. 143, Jan. 2019, pp. 113–22. Pubmed, doi:10.1016/j.apradiso.2018.10.026.
Feng Y, Phipps MD, Phelps TE, Okoye NC, Baumeister JE, Wycoff DE, Dorman EF, Wooten AL, Vlasenko V, Berendzen AF, Wilbur DS, Hoffman TJ, Cutler CS, Ketring AR, Jurisson SS. Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide. Appl Radiat Isot. 2019 Jan;143:113–122.
Published In
Appl Radiat Isot
DOI
EISSN
1872-9800
Publication Date
January 2019
Volume
143
Start / End Page
113 / 122
Location
England
Related Subject Headings
- Selenium Radioisotopes
- Radiopharmaceuticals
- Radionuclide Generators
- Radioligand Assay
- Radioisotopes
- Positron-Emission Tomography
- Phantoms, Imaging
- Nuclear Medicine & Medical Imaging
- Isotopes
- Humans