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Primary adenocarcinoma of the gallbladder presenting as primary gynecologic malignancy: a report of two cases.

Publication ,  Journal Article
Schust, DJ; Moore, DH; Baird, DB; Novotny, DB
Published in: Obstet Gynecol
May 1994

BACKGROUND: Carcinoma metastatic to the uterus from extragenital sites is rare. Such metastatic disease is typically diagnosed at autopsy or in patients with known primary malignancies. This report discusses two cases of primary carcinoma of the gallbladder presenting as abnormalities in gynecologic screening procedures. CASES: A 71-year-old woman presented with postmenopausal bleeding. Uterine curettage revealed poorly differentiated adenocarcinoma of presumed endometrial origin. Intraoperative frozen-section analysis of the uterus showed carcinoma involving the lymphatics, but no primary tumor. Further exploration revealed primary adenocarcinoma of the gallbladder, with widespread metastases. The second case was a 67-year-old asymptomatic woman. Routine cervical cytology showed adenocarcinoma, but tissue studies were negative. She developed jaundice 1 month later. Computed tomography of the upper abdomen revealed a mass in the gallbladder fossa, and needle biopsy of the lesion showed adenocarcinoma. CONCLUSIONS: Metastatic carcinoma of non-genital tract origin may present as primary gynecologic malignancy. The physician should be aware of the implications of both the common and unusual interpretations of screening and diagnostic procedures. When the clinicopathologic presentation is atypical, a thorough knowledge of the differential diagnoses of abnormal test results allows appropriate and expeditious patient management.

Duke Scholars

Published In

Obstet Gynecol

ISSN

0029-7844

Publication Date

May 1994

Volume

83

Issue

5 Pt 2

Start / End Page

831 / 834

Location

United States

Related Subject Headings

  • Vaginal Smears
  • Uterine Neoplasms
  • Obstetrics & Reproductive Medicine
  • Humans
  • Gallbladder Neoplasms
  • Female
  • Aged
  • Adenocarcinoma
  • 3215 Reproductive medicine
  • 1114 Paediatrics and Reproductive Medicine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Schust, D. J., Moore, D. H., Baird, D. B., & Novotny, D. B. (1994). Primary adenocarcinoma of the gallbladder presenting as primary gynecologic malignancy: a report of two cases. Obstet Gynecol, 83(5 Pt 2), 831–834.
Schust, D. J., D. H. Moore, D. B. Baird, and D. B. Novotny. “Primary adenocarcinoma of the gallbladder presenting as primary gynecologic malignancy: a report of two cases.Obstet Gynecol 83, no. 5 Pt 2 (May 1994): 831–34.
Schust DJ, Moore DH, Baird DB, Novotny DB. Primary adenocarcinoma of the gallbladder presenting as primary gynecologic malignancy: a report of two cases. Obstet Gynecol. 1994 May;83(5 Pt 2):831–4.
Schust, D. J., et al. “Primary adenocarcinoma of the gallbladder presenting as primary gynecologic malignancy: a report of two cases.Obstet Gynecol, vol. 83, no. 5 Pt 2, May 1994, pp. 831–34.
Schust DJ, Moore DH, Baird DB, Novotny DB. Primary adenocarcinoma of the gallbladder presenting as primary gynecologic malignancy: a report of two cases. Obstet Gynecol. 1994 May;83(5 Pt 2):831–834.
Journal cover image

Published In

Obstet Gynecol

ISSN

0029-7844

Publication Date

May 1994

Volume

83

Issue

5 Pt 2

Start / End Page

831 / 834

Location

United States

Related Subject Headings

  • Vaginal Smears
  • Uterine Neoplasms
  • Obstetrics & Reproductive Medicine
  • Humans
  • Gallbladder Neoplasms
  • Female
  • Aged
  • Adenocarcinoma
  • 3215 Reproductive medicine
  • 1114 Paediatrics and Reproductive Medicine