Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model.
Publication
, Journal Article
Venkatesan, R; Lin, W; Gurleyik, K; He, YY; Paczynski, RP; Powers, WJ; Hsu, CY
Published in: Magn Reson Med
January 2000
Using a magnetic resonance (MR) imaging method, absolute measurements of in vivo brain water content were obtained in 15 male Long Evans rats that underwent a 90-min focal cerebral ischemia. A strong linear relationship (r = 0.80) with a slope of 1 was observed when correlating MR-measured water content to that obtained with the ex vivo wet/dry measurements. This effective spin-density-based method is the first-reported in vivo absolute quantification of brain tissue water content associated with a pathophysiological state and preliminary findings suggest that a noninvasive measurement of brain water content can be obtained with MRI.
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Published In
Magn Reson Med
DOI
ISSN
0740-3194
Publication Date
January 2000
Volume
43
Issue
1
Start / End Page
146 / 150
Location
United States
Related Subject Headings
- Rats, Long-Evans
- Rats
- Probability
- Nuclear Medicine & Medical Imaging
- Male
- Magnetic Resonance Imaging
- Linear Models
- Disease Models, Animal
- Brain Ischemia
- Brain Edema
Citation
APA
Chicago
ICMJE
MLA
NLM
Venkatesan, R., Lin, W., Gurleyik, K., He, Y. Y., Paczynski, R. P., Powers, W. J., & Hsu, C. Y. (2000). Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model. Magn Reson Med, 43(1), 146–150. https://doi.org/10.1002/(sici)1522-2594(200001)43:1<146::aid-mrm18>3.0.co;2-l
Venkatesan, R., W. Lin, K. Gurleyik, Y. Y. He, R. P. Paczynski, W. J. Powers, and C. Y. Hsu. “Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model.” Magn Reson Med 43, no. 1 (January 2000): 146–50. https://doi.org/10.1002/(sici)1522-2594(200001)43:1<146::aid-mrm18>3.0.co;2-l.
Venkatesan R, Lin W, Gurleyik K, He YY, Paczynski RP, Powers WJ, et al. Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model. Magn Reson Med. 2000 Jan;43(1):146–50.
Venkatesan, R., et al. “Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model.” Magn Reson Med, vol. 43, no. 1, Jan. 2000, pp. 146–50. Pubmed, doi:10.1002/(sici)1522-2594(200001)43:1<146::aid-mrm18>3.0.co;2-l.
Venkatesan R, Lin W, Gurleyik K, He YY, Paczynski RP, Powers WJ, Hsu CY. Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model. Magn Reson Med. 2000 Jan;43(1):146–150.
Published In
Magn Reson Med
DOI
ISSN
0740-3194
Publication Date
January 2000
Volume
43
Issue
1
Start / End Page
146 / 150
Location
United States
Related Subject Headings
- Rats, Long-Evans
- Rats
- Probability
- Nuclear Medicine & Medical Imaging
- Male
- Magnetic Resonance Imaging
- Linear Models
- Disease Models, Animal
- Brain Ischemia
- Brain Edema