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Microwave ablation of cT1a renal cell carcinoma: oncologic and functional outcomes at a single center.

Publication ,  Journal Article
Wilcox Vanden Berg, RN; Calderon, LP; LaRussa, S; Enobakhare, O; Craig, K; Del Pizzo, J; McClure, TD
Published in: Clin Imaging
August 2021

PURPOSE: Percutaneous ablation is an established alternative to surgical intervention for small renal masses. Radiofrequency and cryoablation have been studied extensively in the literature. To date, series assessing the efficacy and safety of microwave ablation (MWA) are limited. We present a cohort of 110 renal tumors treated with MWA. METHODS: A review of the medical record between January 2015 and July 2019 was performed, retrospectively identifying 101 patients (110 tumors). All ablations were performed by a single board-certified urologist/interventional radiologist. Demographic information, intraoperative, postoperative, and follow-up surveillance data were recorded. RESULTS: Median (IQR) age was 69.7 years (60.8-77.0); 27 (24%) were female. Median (IQR) BMI was 27.0 (25.1-30.2) and Charleston Comorbidity Index was 5.0 (4.0-6.0). 82 tumors were biopsy-confirmed renal cell carcinoma/oncocytic neoplasms. Median (IQR) tumor size was 2.0 cm (1.5-2.6). Median (IQR) RENAL nephrometry score was 6.0 (5.0-8.0). Technical success was achieved in all patients and all but one patient were discharged on the same day. Median (IQR) eGFR at baseline and 1 year were 71.9 mL/min/1.73 m2 (56.5-82) and 63.0 mL/min/1.73 m2 (54.0-78.2); the difference was -5.3 (p = 0.12). Two Clavien-Dindo type-I complications, one type-II complication, and one type-III complication were experienced in this cohort. Median radiographic follow-up was 376.5 days with 2 tumors (2.4% of RCC/oncocytic neoplasms) having recurred to date. CONCLUSIONS: MWA is a safe and efficacious treatment option for small renal masses with minimal adverse events and low rates of recurrence in this cohort of 101 patients. Continued follow-up is needed to assess long-term outcomes.

Duke Scholars

Published In

Clin Imaging

DOI

EISSN

1873-4499

Publication Date

August 2021

Volume

76

Start / End Page

199 / 204

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Neoplasm Recurrence, Local
  • Microwaves
  • Male
  • Kidney Neoplasms
  • Humans
  • Female
  • Catheter Ablation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wilcox Vanden Berg, R. N., Calderon, L. P., LaRussa, S., Enobakhare, O., Craig, K., Del Pizzo, J., & McClure, T. D. (2021). Microwave ablation of cT1a renal cell carcinoma: oncologic and functional outcomes at a single center. Clin Imaging, 76, 199–204. https://doi.org/10.1016/j.clinimag.2021.04.016
Wilcox Vanden Berg, Rand N., Lina Posada Calderon, Samuel LaRussa, Osamade Enobakhare, Kiersten Craig, Joseph Del Pizzo, and Timothy D. McClure. “Microwave ablation of cT1a renal cell carcinoma: oncologic and functional outcomes at a single center.Clin Imaging 76 (August 2021): 199–204. https://doi.org/10.1016/j.clinimag.2021.04.016.
Wilcox Vanden Berg RN, Calderon LP, LaRussa S, Enobakhare O, Craig K, Del Pizzo J, et al. Microwave ablation of cT1a renal cell carcinoma: oncologic and functional outcomes at a single center. Clin Imaging. 2021 Aug;76:199–204.
Wilcox Vanden Berg, Rand N., et al. “Microwave ablation of cT1a renal cell carcinoma: oncologic and functional outcomes at a single center.Clin Imaging, vol. 76, Aug. 2021, pp. 199–204. Pubmed, doi:10.1016/j.clinimag.2021.04.016.
Wilcox Vanden Berg RN, Calderon LP, LaRussa S, Enobakhare O, Craig K, Del Pizzo J, McClure TD. Microwave ablation of cT1a renal cell carcinoma: oncologic and functional outcomes at a single center. Clin Imaging. 2021 Aug;76:199–204.
Journal cover image

Published In

Clin Imaging

DOI

EISSN

1873-4499

Publication Date

August 2021

Volume

76

Start / End Page

199 / 204

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Neoplasm Recurrence, Local
  • Microwaves
  • Male
  • Kidney Neoplasms
  • Humans
  • Female
  • Catheter Ablation