Changing the landscape of non-small cell lung cancer disparities.

Journal Article (Journal Article)

In the United States, lung and bronchus cancers are the second most common types of cancer and are responsible for the largest number of deaths from cancer, with African Americans suffering disproportionately from lung and bronchus cancers. This disparity likely results from a complex interplay among social, psycho-social, lifestyle, environmental, health system, and biological determinants of health. Toward improving outcomes for lung cancer patients of all races and ethnicities and mitigating lung cancer disparities, in this commentary, we bring forward biological factors that contribute to lung cancer disparities, efforts to identify, functionally characterize, and modulate novel ancestry-related RNA splicing-related targets in lung cancer for precision intervention, and translational and clinical research needs to improve outcomes for lung cancer patients of all races and ethnicities and mitigate lung cancer disparities.

Full Text

Duke Authors

Cited Authors

  • Odera, JO; Abo, MA; Patierno, SR; Clarke, JM; Freedman, JA

Published Date

  • 2021

Published In

  • J Cancer Biol

Volume / Issue

  • 2 / 2

Start / End Page

  • 33 - 38

PubMed ID

  • 35929605

Pubmed Central ID

  • PMC9347607

Digital Object Identifier (DOI)

  • 10.46439/cancerbiology.2.020


  • eng

Conference Location

  • United States