Targeted Neoadjuvant Intra-arterial Chemotherapy in Lacrimal Gland Adenoid Cystic Carcinoma: A Histological Correlation Using Apoptotic Tumor Markers.
Publication
, Journal Article
Maniar, A; Saqi, A; Troob, SH; Belinsky, I; Charles, NC; Gobin, YP; Marr, BP
Published in: Ophthalmic Plast Reconstr Surg
January 2022
Neoadjuvant intra-arterial cytoreductive chemotherapy is used for the treatment of lacrimal gland adenoid cystic carcinomas (ACC) to improve outcomes in this condition with an otherwise dismal prognosis. We share our experience in the management of an advanced case of ACC using a novel, highly targeted intra-arterial cytoreductive chemotherapy delivery technique involving both the internal and external carotid circulation, with an attempt to correlate the effect histologically. Refinement of the chemotherapy delivery using the tumor's vascular anatomy and appropriate blood vessel selection may lead to future globe sparing procedures without compromising survival.
Duke Scholars
Published In
Ophthalmic Plast Reconstr Surg
DOI
EISSN
1537-2677
Publication Date
January 2022
Volume
38
Issue
1
Start / End Page
e28 / e33
Location
United States
Related Subject Headings
- Ophthalmology & Optometry
- Neoadjuvant Therapy
- Lacrimal Apparatus Diseases
- Lacrimal Apparatus
- Humans
- Eye Neoplasms
- Carcinoma, Adenoid Cystic
- Biomarkers, Tumor
- 3212 Ophthalmology and optometry
- 1113 Opthalmology and Optometry
Citation
APA
Chicago
ICMJE
MLA
NLM
Maniar, A., Saqi, A., Troob, S. H., Belinsky, I., Charles, N. C., Gobin, Y. P., & Marr, B. P. (2022). Targeted Neoadjuvant Intra-arterial Chemotherapy in Lacrimal Gland Adenoid Cystic Carcinoma: A Histological Correlation Using Apoptotic Tumor Markers. Ophthalmic Plast Reconstr Surg, 38(1), e28–e33. https://doi.org/10.1097/IOP.0000000000002071
Maniar, Arpita, Anjali Saqi, Scott H. Troob, Irina Belinsky, Norman C. Charles, Y Pierre Gobin, and Brian P. Marr. “Targeted Neoadjuvant Intra-arterial Chemotherapy in Lacrimal Gland Adenoid Cystic Carcinoma: A Histological Correlation Using Apoptotic Tumor Markers.” Ophthalmic Plast Reconstr Surg 38, no. 1 (January 2022): e28–33. https://doi.org/10.1097/IOP.0000000000002071.
Maniar A, Saqi A, Troob SH, Belinsky I, Charles NC, Gobin YP, et al. Targeted Neoadjuvant Intra-arterial Chemotherapy in Lacrimal Gland Adenoid Cystic Carcinoma: A Histological Correlation Using Apoptotic Tumor Markers. Ophthalmic Plast Reconstr Surg. 2022 Jan;38(1):e28–33.
Maniar, Arpita, et al. “Targeted Neoadjuvant Intra-arterial Chemotherapy in Lacrimal Gland Adenoid Cystic Carcinoma: A Histological Correlation Using Apoptotic Tumor Markers.” Ophthalmic Plast Reconstr Surg, vol. 38, no. 1, Jan. 2022, pp. e28–33. Pubmed, doi:10.1097/IOP.0000000000002071.
Maniar A, Saqi A, Troob SH, Belinsky I, Charles NC, Gobin YP, Marr BP. Targeted Neoadjuvant Intra-arterial Chemotherapy in Lacrimal Gland Adenoid Cystic Carcinoma: A Histological Correlation Using Apoptotic Tumor Markers. Ophthalmic Plast Reconstr Surg. 2022 Jan;38(1):e28–e33.
Published In
Ophthalmic Plast Reconstr Surg
DOI
EISSN
1537-2677
Publication Date
January 2022
Volume
38
Issue
1
Start / End Page
e28 / e33
Location
United States
Related Subject Headings
- Ophthalmology & Optometry
- Neoadjuvant Therapy
- Lacrimal Apparatus Diseases
- Lacrimal Apparatus
- Humans
- Eye Neoplasms
- Carcinoma, Adenoid Cystic
- Biomarkers, Tumor
- 3212 Ophthalmology and optometry
- 1113 Opthalmology and Optometry