Neuromodulation therapy for atrial fibrillation.
Journal Article (Journal Article;Review)
Atrial fibrillation has a multifactorial pathophysiology influenced by cardiac autonomic innervation. Both sympathetic and parasympathetic influences are profibrillatory. Innovative therapies targeting the neurocardiac axis include catheter ablation or pharmacologic suppression of ganglionated plexi, renal sympathetic denervation, low-level vagal stimulation, and stellate ganglion blockade. To date, these therapies have variable efficacy. As our understanding of atrial fibrillation and the cardiac nervous system expands, our approach to therapeutic neuromodulation will continue evolving for the benefit of those with AF.
- Karatela, MF; Fudim, M; Mathew, JP; Piccini, JP
- January 2023
Volume / Issue
- 20 / 1
Start / End Page
- 100 - 111
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)
- United States