Implementation of an At-home Blood Pressure Measurement Protocol in a Hypertension Management Clinical Trial During the COVID-19 Pandemic.

Journal Article (Journal Article)

BACKGROUND: The Dietary Approaches to Stop Hypertension eating plan is an evidence-based treatment of hypertension; however, adherence to the Dietary Approaches to Stop Hypertension is low. To improve adherence to the Dietary Approaches to Stop Hypertension among adults with hypertension, we designed Nourish, a 2-arm, 12-month randomized controlled trial. The COVID-19 pandemic necessitated a change from in-person to remotely delivered visits, requiring substantial protocol modifications to measure blood pressure accurately and safely for secondary outcome data. PURPOSE: The purpose of this article is to describe the implementation of an at-home blood pressure measurement protocol for the Nourish trial. CONCLUSION: Our investigator team and study staff developed and implemented a robust and feasible blood pressure measurement protocol to be executed within an at-home format. CLINICAL IMPLICATIONS: The described blood pressure measurement protocol provides a framework for use in future clinical trials and clinical settings in which a remote visit is preferred or required.

Full Text

Duke Authors

Cited Authors

  • Miller, HN; Berger, MB; Askew, S; Trefney, E; Tyson, C; Svetkey, L; Bennett, GG; Steinberg, DM

Published Date

  • September 2022

Published In

Volume / Issue

  • 37 / 5

Start / End Page

  • 475 - 481

PubMed ID

  • 35467561

Pubmed Central ID

  • PMC9378583

Electronic International Standard Serial Number (EISSN)

  • 1550-5049

Digital Object Identifier (DOI)

  • 10.1097/JCN.0000000000000927


  • eng

Conference Location

  • United States