Effect of a 17alpha-(3-hydroxypropyl)-17beta-acetyl substituent pattern on the glucocorticoid and progestin receptor binding of 11beta-arylestra-4,9-dien-3-ones.

Journal Article (Journal Article)

[structure: see text]. Replacing the 17alpha-acetoxy substituent in an antiprogestational 17beta-acetyl-11beta-arylestra-4,9-dien-3-one by 3-hydroxypropyl significantly diminished glucocorticoid receptor binding with little effect on progestin receptor binding.

Full Text

Duke Authors

Cited Authors

  • Cook, CE; Raje, P; Lee, DY; Kepler, JA

Published Date

  • April 5, 2001

Published In

Volume / Issue

  • 3 / 7

Start / End Page

  • 1013 - 1016

PubMed ID

  • 11277783

International Standard Serial Number (ISSN)

  • 1523-7060


  • eng

Conference Location

  • United States