Orthostatic hypotension after delta 9-tetrahydrocannabinol marihuana inhalation.

Journal Article (Journal Article)

3 male glaucoma subjects experienced orthostatic hypotension within 10 min after completing 2% delta 9-THC ranging from 57 to 233 ng/ml were found 5 min after smoking. Peripheral venodilation appeared responsible for the precipitous decrease in systolic blood pressure in all 3 subjects. These orthostatic episodes which clinically simulated the typical 'faint' were characterized by the absence of tachycardia and their relief by assuming a reclining position. The postural hypotension occurred despite differences in inhalation technique, level of delta (9)-THC present in plasma, previous marihuana experience of body habitus.

Full Text

Duke Authors

Cited Authors

  • Merritt, JC; Cook, CE; Davis, KH

Published Date

  • 1982

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 124 - 128

PubMed ID

  • 6283454

International Standard Serial Number (ISSN)

  • 0030-3747

Digital Object Identifier (DOI)

  • 10.1159/000265183

Language

  • eng

Conference Location

  • Switzerland