Heart Failure with Preserved Ejection Fraction in Older Adults.

Journal Article (Journal Article;Review)

Most elderly patients, particularly women, who have heart failure, have a preserved ejection fraction. Patients with this syndrome have severe symptoms of exercise intolerance, frequent hospitalizations, and increased mortality. Despite the importance of heart failure with preserved ejection fraction (HFpEF), the understanding of its pathophysiology is incomplete, and optimal treatment remains largely undefined. Unlike the management of HFrEF, there is a paucity of large evidence-based trials demonstrating morbidity and mortality benefit for the treatment of HFpEF. An update is presented on information regarding pathophysiology, diagnosis, management, and future directions in this important and growing disorder.

Full Text

Duke Authors

Cited Authors

  • Upadhya, B; Kitzman, DW

Published Date

  • July 2017

Published In

Volume / Issue

  • 13 / 3

Start / End Page

  • 485 - 502

PubMed ID

  • 28602367

Pubmed Central ID

  • PMC5546159

International Standard Serial Number (ISSN)

  • 1551-7136

Digital Object Identifier (DOI)

  • 10.1016/j.hfc.2017.02.005


  • eng

Conference Location

  • United States