"High probability" perfusion lung scans in pulmonary venoocclusive disease.

Journal Article (Journal Article)

"High-probability" ventilation/perfusion (V/Q) lung scans generally indicate proximal pulmonary arterial occlusion by thromboemboli or, rarely, other processes such as tumors, fibrosing mediastinitis, or vasculitis. In this report we describe three patients with high probability V/Q scans in whom pulmonary angiography failed to demonstrate arterial occlusion. All three patients were determined to have pulmonary venoocclusive disease (PVOD). In two patients, a tissue diagnosis of PVOD was made, in one case with explanted tissue taken after a successful heart-lung transplant and in the other case with tissue taken at autopsy. PVOD in the third patient was diagnosed with pulmonary venography. A potential explanation for the discrepancy between perfusion lung scan and pulmonary angiographic findings in PVOD is discussed.

Full Text

Duke Authors

Cited Authors

  • Bailey, CL; Channick, RN; Auger, WR; Fedullo, PF; Kerr, KM; Yung, GL; Rubin, LJ

Published Date

  • November 2000

Published In

Volume / Issue

  • 162 / 5

Start / End Page

  • 1974 - 1978

PubMed ID

  • 11069842

International Standard Serial Number (ISSN)

  • 1073-449X

Digital Object Identifier (DOI)

  • 10.1164/ajrccm.162.5.2003045


  • eng

Conference Location

  • United States