Cavitary lung nodules as an extraintestinal manifestation of ulcerative colitis.

Journal Article (Journal Article)

A man in his 30s with ulcerative colitis (UC) on immunosuppressive agents and extensive travel history presented with subacute dyspnoea and dry cough. CT of the chest demonstrated numerous cavitary pulmonary nodules. An extensive infectious, malignant and autoimmune evaluation was pursued, ultimately with histopathology most consistent with necrobiotic lung nodules as an extraintestinal manifestation of UC. Steroids and ustekinumab were initiated with improvement in symptoms and resolution of cavitary lesions on follow-up imaging. In a patient with inflammatory bowel disease and cavitary lung lesions, necrobiotic lung nodules should be considered, particularly when evaluation for infectious causes is negative.

Full Text

Duke Authors

Cited Authors

  • Paul, N; Lazarev, M; Montemayor, K; Horne, AJ

Published Date

  • September 23, 2022

Published In

Volume / Issue

  • 15 / 9

PubMed ID

  • 36150725

Pubmed Central ID

  • PMC9511551

Electronic International Standard Serial Number (EISSN)

  • 1757-790X

Digital Object Identifier (DOI)

  • 10.1136/bcr-2022-251976


  • eng

Conference Location

  • England